Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.44 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | PBK | Q96KB5 | 4/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3314984 | 0.88 | — | — | |
| SCHEMBL148965 | 0.82 | SLC6A1 (0.50) | MAPK1OPRK1SLC6A1SLC6A11TSHR | |
| SCHEMBL1968950 | 0.82 | SLC6A1 (0.50) | MAPK1OPRK1SLC6A1SLC6A11TSHR | |
| SCHEMBL475548 | 0.82 | SLC6A1 (0.50) | MAPK1OPRK1SLC6A1SLC6A11TSHR | |
| SCHEMBL23139818 | 0.80 | MAPK1 (0.47) | MAPK1OPRK1SLC6A1SLC6A11TSHR | |
| SCHEMBL1006531 | 0.80 | MAPK1 (0.50) | MAPK1OPRK1SLC6A1SLC6A11TSHR | |
| SCHEMBL17902608 | 0.80 | MAPK1 (0.47) | MAPK1OPRK1SLC6A1SLC6A11TSHR | |
| SCHEMBL16561741 | 0.80 | KDM4E (0.52) | MAPK1OPRK1SLC6A1SLC6A11KDM4E | |
| SCHEMBL12260711 | 0.80 | EPHX1 (0.66) | MAPK1OPRK1SLC6A1SLC6A11TSHR | |
| Hydrochloric Acid SCHEMBL17560394 | 0.80 | SLC6A1 (0.48) | MAPK1OPRK1SLC6A1SLC6A11TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005016883-A2 | ACRYLAMIDE DERIVATIVES AS VLA-1 INTEGRIN ANTAGONISTS AND USES THEREOF | ICOS CORPORATION (US) | 2005-02-24 | — | — | WO | claimed |
| WO-2005016883-A2 | ACRYLAMIDE DERIVATIVES AS VLA-1 INTEGRIN ANTAGONISTS AND USES THEREOF | ICOS CORPORATION (US) | 2005-02-24 | — | — | WO | disclosed |