Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 5/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 5/20 | 0.39 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6487780 | 0.96 | MCL1 (0.47) | MCL1FFAR4FFAR1PLA2G2A | |
| SCHEMBL6489678 | 0.92 | MCL1 (0.41) | MCL1PLA2G2ATHRBTHRAP2RX3 | |
| SCHEMBL6498711 | 0.91 | MCL1 (0.43) | MCL1FFAR4FFAR1PLA2G2A | |
| SCHEMBL6488344 | 0.91 | MCL1 (0.47) | MCL1FFAR4FFAR1PLA2G2APLA2G4B | |
| SCHEMBL6503545 | 0.88 | MCL1 (0.43) | MCL1FFAR4FFAR1PLA2G2A | |
| SCHEMBL6501386 | 0.88 | MCL1 (0.48) | MCL1FFAR4FFAR1PLA2G2A | |
| SCHEMBL6495250 | 0.84 | RARB (0.45) | PLA2G4B | |
| SCHEMBL6488487 | 0.84 | PDE2A (0.39) | THRBTHRA | |
| SCHEMBL6487942 | 0.84 | MCL1 (0.42) | MCL1PLA2G2ATHRBTHRAP2RX3 | |
| SCHEMBL6488960 | 0.83 | PTPN11 (0.44) | PLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | SLC5A1, SLC5A2, G6PD | MCL1 806/4885FFAR4 960/4885FFAR1 1226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.