SCHEMBL6498211

SCHEMBL6498211

[CH2]NC(=O)C1=CCOO1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8742065 0.78
SCHEMBL6150942 0.71
Methane SCHEMBL27759073 0.71
SCHEMBL6872594 0.71
SCHEMBL4067354 0.71
Ammonia Solution, Strong SCHEMBL27607319 0.71
Pyrrole SCHEMBL27607284 0.64
SCHEMBL29035804 0.61 KMT2A (0.36)
SCHEMBL6973301 0.59
SCHEMBL4753908 0.58

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005016883-A2 ACRYLAMIDE DERIVATIVES AS VLA-1 INTEGRIN ANTAGONISTS AND USES THEREOF ICOS CORPORATION (US) 2005-02-24 WO claimed