Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 11/20 | 0.55 |
| ▸ | AAK1 | Q2M2I8 | 10/20 | 0.53 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6497735 | 0.84 | IMPDH2 (0.58) | IMPDH2AAK1IMPDH1 | |
| SCHEMBL6485816 | 0.78 | IMPDH2 (0.65) | IMPDH2AAK1IMPDH1 | |
| SCHEMBL5613894 | 0.77 | IMPDH2 (0.73) | IMPDH2AAK1IMPDH1 | |
| SCHEMBL6487637 | 0.77 | IMPDH2 (0.64) | IMPDH2AAK1IMPDH1 | |
| SCHEMBL6501585 | 0.76 | IMPDH2 (0.63) | IMPDH2AAK1IMPDH1 | |
| SCHEMBL6498132 | 0.75 | IMPDH2 (0.61) | IMPDH2AAK1IMPDH1 | |
| SCHEMBL1473366 | 0.74 | IMPDH2 (1.00) | IMPDH2AAK1IMPDH1 | |
| SCHEMBL1476067 | 0.73 | IMPDH2 (0.79) | IMPDH2AAK1IMPDH1 | |
| SCHEMBL6487358 | 0.73 | IMPDH2 (0.61) | IMPDH2AAK1IMPDH1 | |
| SCHEMBL6486704 | 0.73 | IMPDH2 (0.63) | IMPDH2AAK1IMPDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6867299-B2 | Inosine monophosphate dehydrogenase (IMPDH); use as immunosuppressants, anticancer agents and antiviral agents | HOFFMANN-LA ROCHE INC. (US) | 2005-03-15 | — | — | US | disclosed |