Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | MIF | P14174 | 2/20 | 0.36 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | ACP3 | P15309 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6498343 | 1.00 | MAPT (0.40) | MAPTGAAGFERHTR2AHTR2B | |
| SCHEMBL21495637 | 1.00 | MAPT (0.40) | MAPTGAAGFERHTR2AHTR2B | |
| SCHEMBL21495218 | 0.90 | MAPT (0.38) | MAPTGAAHTR2AHTR2BHTR2C | |
| SCHEMBL21495219 | 0.90 | MAPT (0.38) | MAPTGAAHTR2AHTR2BHTR2C | |
| SCHEMBL6500395 | 0.81 | MAPT (0.45) | MAPTGAAGFERDAOLMNA | |
| SCHEMBL6500399 | 0.81 | MAPT (0.45) | MAPTGAAGFERDAOLMNA | |
| SCHEMBL3185063 | 0.77 | IDO1 (0.39) | MAPTGAAGFERHTR2AHTR2B | |
| SCHEMBL3185070 | 0.77 | IDO1 (0.39) | MAPTGAAGFERHTR2AHTR2B | |
| SCHEMBL3185075 | 0.77 | IDO1 (0.39) | MAPTGAAGFERHTR2AHTR2B | |
| SCHEMBL6501316 | 0.77 | GAA (0.42) | MAPTGAAGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019202459-A1 | USE OF 4-SUBSTITUTED PHENYLAMIDINE COMPOUNDS FOR CONTROLLING DISEASE RUST DISEASES IN PLANTS | PI INDUSTRIES LTD. (IN) | 2019-10-24 | — | — | WO | claimed |
| US-6893650-B1 | N2-phenylamidine derivatives | BAYER CROPSCIENCE GMBH (DE) | 2005-05-17 | — | — | US | disclosed |
| EP-1150944-B1 | N2-PHENYLAMIDINE DERIVATIVES | BAYER CROPSCIENCE GMBH (DE) | 2003-08-20 | — | — | EP | disclosed |