Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALPG | P10696 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6500395 | 1.00 | MAPT (0.45) | MAPTNPSR1HTTLMNARAB9A | |
| SCHEMBL21495637 | 0.81 | MAPT (0.40) | MAPTLMNAGFERGAADAO | |
| SCHEMBL6498343 | 0.81 | MAPT (0.40) | MAPTLMNAGFERGAADAO | |
| SCHEMBL15022922 | 0.81 | SLC6A2 (0.47) | MAPTNPSR1RAB9ACYP3A4GFER | |
| SCHEMBL6498345 | 0.81 | MAPT (0.40) | MAPTLMNAGFERGAADAO | |
| SCHEMBL15022920 | 0.81 | SLC6A2 (0.47) | MAPTNPSR1RAB9ACYP3A4GFER | |
| SCHEMBL6490179 | 0.76 | RAB9A (0.49) | MAPTNPSR1HTTLMNARAB9A | |
| SCHEMBL3185075 | 0.74 | IDO1 (0.39) | MAPTHTTLMNAL3MBTL1GFER | |
| SCHEMBL3185070 | 0.74 | IDO1 (0.39) | MAPTHTTLMNAL3MBTL1GFER | |
| SCHEMBL3185063 | 0.74 | IDO1 (0.39) | MAPTHTTLMNAL3MBTL1GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6893650-B1 | N2-phenylamidine derivatives | BAYER CROPSCIENCE GMBH (DE) | 2005-05-17 | — | — | US | disclosed |
| EP-1150944-B1 | N2-PHENYLAMIDINE DERIVATIVES | BAYER CROPSCIENCE GMBH (DE) | 2003-08-20 | — | — | EP | disclosed |