Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 15/20 | 0.46 |
| ▸ | PPARD | Q03181 | 12/20 | 0.46 |
| ▸ | PPARG | P37231 | 14/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6498702 | 0.91 | PPARG (0.52) | PPARAPPARDPPARG | |
| SCHEMBL7684941 | 0.87 | PPARA (0.52) | PPARAPPARDPPARG | |
| SCHEMBL6503008 | 0.87 | PPARG (0.48) | PPARAPPARDPPARG | |
| SCHEMBL6494086 | 0.84 | PPARA (0.54) | PPARAPPARDPPARG | |
| SCHEMBL6505578 | 0.83 | PPARG (0.41) | PPARAPPARDPPARG | |
| SCHEMBL6496502 | 0.83 | PPARA (0.39) | PPARAPPARDPPARGALDH1A1LMNA | |
| SCHEMBL6497873 | 0.81 | PPARA (0.50) | PPARAPPARDPPARG | |
| SCHEMBL6506146 | 0.79 | EPHX2 (0.37) | PPARAPPARDPPARG | |
| SCHEMBL6527212 | 0.77 | PPARA (0.45) | PPARAPPARDPPARG | |
| SCHEMBL6497310 | 0.77 | PPARG (0.54) | PPARAPPARDPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |