Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | WDR5 | P61964 | 3/20 | 0.36 |
| ▸ | PDE4A | P27815 | 2/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 5/20 | 0.36 |
| ▸ | PPARG | P37231 | 6/20 | 0.35 |
| ▸ | PPARD | Q03181 | 3/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.34 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.34 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6496225 | 0.92 | WDR5 (0.36) | EPHX2WDR5PDE4BPPARAPPARG | |
| SCHEMBL6498650 | 0.91 | EPHX2 (0.40) | EPHX2WDR5PDE4APDE4BPDE4C | |
| SCHEMBL6497549 | 0.89 | WDR5 (0.39) | EPHX2WDR5PDE4APDE4BPDE4C | |
| SCHEMBL6496502 | 0.89 | PPARA (0.39) | WDR5PPARAPPARGPPARD | |
| SCHEMBL6505578 | 0.88 | PPARG (0.41) | EPHX2PPARAPPARGPPARD | |
| SCHEMBL6495937 | 0.88 | WDR5 (0.40) | EPHX2WDR5PDE4APDE4BPDE4C | |
| SCHEMBL6507195 | 0.86 | PPARG (0.40) | EPHX2WDR5PDE4APDE4BPDE4C | |
| SCHEMBL6503008 | 0.86 | PPARG (0.48) | PPARAPPARGPPARD | |
| SCHEMBL6507594 | 0.81 | ADORA2A (0.38) | PPARAPPARGPPARD | |
| SCHEMBL7684246 | 0.81 | SHMT1 (0.39) | WDR5PDE4BPPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |