Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 6/20 | 0.49 |
| ▸ | ICAM1 | P05362 | 6/20 | 0.49 |
| ▸ | ITGAL | P20701 | 6/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | USP7 | Q93009 | 2/20 | 0.41 |
| ▸ | USP47 | Q96K76 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.38 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5830782 | 0.89 | ITGB2 (0.53) | ITGB2ICAM1ITGALLMNAALDH1A1 | |
| SCHEMBL5829924 | 0.87 | ITGAL (0.64) | ITGB2ICAM1ITGALLMNAALDH1A1 | |
| SCHEMBL5830016 | 0.84 | LMNA (0.51) | ITGB2ICAM1ITGALLMNAALDH1A1 | |
| SCHEMBL5830388 | 0.84 | ITGB2 (0.51) | ITGB2ICAM1ITGALLMNAALDH1A1 | |
| SCHEMBL5830818 | 0.84 | LMNA (0.52) | ITGB2ICAM1ITGALLMNAALDH1A1 | |
| SCHEMBL5830427 | 0.83 | ITGB2 (0.52) | ITGB2ICAM1ITGALLMNAALDH1A1 | |
| SCHEMBL5830356 | 0.83 | ITGB2 (0.50) | ITGB2ICAM1ITGALLMNAALDH1A1 | |
| SCHEMBL6199570 | 0.82 | LMNA (0.51) | ITGB2ICAM1ITGALLMNAALDH1A1 | |
| SCHEMBL6498759 | 0.82 | LMNA (0.51) | ITGB2ICAM1ITGALLMNAALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL6201123 | 0.80 | ITGB2 (0.47) | ITGB2ICAM1ITGALLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6878700-B1 | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds | ABBOTT LABORATORIES (US) | 2005-04-12 | — | — | US | disclosed |