Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 8/20 | 0.43 |
| ▸ | RAB9A | P51151 | 8/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | ITGAL | P20701 | 3/20 | 0.41 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.41 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6498757 | 1.00 | CAPN1 (0.47) | CAPN1NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL6498135 | 0.91 | CAPN1 (0.47) | CAPN1NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL6498130 | 0.91 | CAPN1 (0.47) | CAPN1NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL8298766 | 0.91 | CAPN1 (0.47) | CAPN1NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL6498794 | 0.87 | CAPN1 (0.49) | CAPN1NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL6498797 | 0.87 | CAPN1 (0.49) | CAPN1NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL6503200 | 0.84 | ITGB2 (0.49) | CAPN1NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL6503201 | 0.84 | ITGB2 (0.49) | CAPN1NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL8296931 | 0.83 | SMN1; SMN2 (0.47) | CAPN1NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL6495765 | 0.79 | CAPN1 (0.47) | CAPN1NPC1RAB9AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005016883-A2 | ACRYLAMIDE DERIVATIVES AS VLA-1 INTEGRIN ANTAGONISTS AND USES THEREOF | ICOS CORPORATION (US) | 2005-02-24 | — | — | WO | disclosed |