Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5010857 | 0.93 | IMPDH2 (0.67) | IMPDH2IMPDH1 | |
| SCHEMBL5010873 | 0.92 | IMPDH2 (0.68) | IMPDH2IMPDH1 | |
| SCHEMBL5013902 | 0.91 | IMPDH2 (0.70) | IMPDH2IMPDH1 | |
| SCHEMBL5011036 | 0.91 | IMPDH2 (0.73) | IMPDH2IMPDH1 | |
| SCHEMBL5010993 | 0.90 | IMPDH2 (0.67) | IMPDH2IMPDH1 | |
| SCHEMBL5010861 | 0.90 | IMPDH2 (0.69) | IMPDH2IMPDH1 | |
| SCHEMBL5010858 | 0.89 | IMPDH2 (0.66) | IMPDH2IMPDH1 | |
| SCHEMBL5010905 | 0.89 | IMPDH2 (0.66) | IMPDH2IMPDH1 | |
| SCHEMBL5013906 | 0.88 | IMPDH2 (0.67) | IMPDH2IMPDH1 | |
| SCHEMBL5010205 | 0.88 | IMPDH2 (0.67) | IMPDH2IMPDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6867299-B2 | Inosine monophosphate dehydrogenase (IMPDH); use as immunosuppressants, anticancer agents and antiviral agents | HOFFMANN-LA ROCHE INC. (US) | 2005-03-15 | — | — | US | disclosed |