Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ACACB | O00763 | 1/20 | 0.44 |
| ▸ | ACACA | Q13085 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 2/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6491894 | 0.85 | KMT2A (0.52) | ALDH1A1KDM4ETSHRKMT2AACACB | |
| SCHEMBL6479986 | 0.85 | KMT2A (0.46) | ALDH1A1KDM4ESMN1; SMN2KMT2AACACB | |
| SCHEMBL6480776 | 0.83 | KMT2A (0.53) | ALDH1A1KDM4ETSHRKMT2AACACB | |
| SCHEMBL6481517 | 0.82 | KMT2A (0.53) | ALDH1A1KDM4ETSHRSMN1; SMN2KMT2A | |
| SCHEMBL18854912 | 0.81 | KMT2A (0.66) | ALDH1A1KDM4ETSHRSMN1; SMN2KMT2A | |
| SCHEMBL6492275 | 0.80 | ACACB (0.58) | ALDH1A1KDM4ETSHRSMN1; SMN2KMT2A | |
| SCHEMBL6490976 | 0.80 | KMT2A (0.36) | ALDH1A1KDM4ETSHRSMN1; SMN2KMT2A | |
| SCHEMBL6480462 | 0.80 | KMT2A (0.45) | ALDH1A1KDM4ETSHRKMT2AACACB | |
| SCHEMBL6481434 | 0.79 | LMNA (0.49) | ALDH1A1KDM4ETSHRSMN1; SMN2KMT2A | |
| SCHEMBL6479149 | 0.79 | KMT2A (0.49) | ALDH1A1KDM4ETSHRKMT2AACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005007643-A1 | NOVEL ACRIDINE DERIVATIVES AND USE THEREOF AS MEDICAMENTS | ZENTARIS GMBH (DE) | 2005-01-27 | — | — | WO | claimed |
| WO-2005007643-A1 | NOVEL ACRIDINE DERIVATIVES AND USE THEREOF AS MEDICAMENTS | ZENTARIS GMBH (DE) | 2005-01-27 | — | — | WO | disclosed |