⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28342310 | 0.97 | GAA (0.50) | — | |
| SCHEMBL28745990 | 0.97 | GAA (0.50) | — | |
| SCHEMBL28358909 | 0.97 | GAA (0.50) | — | |
| SCHEMBL26684 | 0.97 | — | — | |
| Iodide SCHEMBL28618721 | 0.93 | — | — | |
| SCHEMBL2323786 | 0.93 | — | — | |
| Lithium SCHEMBL30387988 | 0.93 | — | — | |
| Ammonia Solution, Strong SCHEMBL6253681 | 0.93 | — | — | |
| Hydrochloric Acid SCHEMBL4434111 | 0.93 | — | — | |
| Phosphine SCHEMBL11162239 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1345308-A | Acetylenic alpha-amino acid based sulfonamide hydroxamic acid TACE inhibitors | AMERICAN CYANAMID CO (US) | 2002-04-17 | — | — | CN | claimed |
| CN-117142982-A | Synthesis method of 2-iso-nitrosopropiophenone | 沈阳思拓新材料技术有限公司 | 2023-12-01 | — | — | CN | disclosed |
| US-6908996-B2 | Compounds and method for preparing 3-methylcephams | IMPERIAL COLLEGE OF LONDON (GB) | 2005-06-21 | — | — | US | disclosed |
| CN-1550496-A | Acetylenic alpha-amino acid-based sulfamide hydroxamic acid TACE inhibitors | ���Ͽع�����˾ | 2004-12-01 | — | — | CN | disclosed |
| US-6683176-B2 | FOR USE IN PRODUCING AMINO ACID DERIVATIVE ANTIBIOTICS | COOPER CONSULTING | 2004-01-27 | — | — | US | disclosed |
| EP-1183262-A4 | INTERMEDIATES FOR AND SYNTHESIS OF 3-METHYLENE CEPHAMS | COOPER CONSULTING INC (US) | 2003-04-09 | — | — | EP | disclosed |
| CN-1345308-A | Acetylenic alpha-amino acid based sulfonamide hydroxamic acid TACE inhibitors | AMERICAN CYANAMID CO (US) | 2002-04-17 | — | — | CN | disclosed |
| EP-1183262-A1 | INTERMEDIATES FOR AND SYNTHESIS OF 3-METHYLENE CEPHAMS | Cooper Consulting Inc. (US) | 2002-03-06 | — | — | EP | disclosed |
| WO-2001060828-A1 | INTERMEDIATES FOR AND SYNTHESIS OF 3-METHYLENE CEPHAMS | COOPER CONSULTING INC. (US) | 2001-08-23 | — | — | WO | disclosed |