SCHEMBL650050

SCHEMBL650050

CCCCn1c(-c2ccccc2)nc(Br)c1CN(Cc1ccc(OC(F)F)cc1)Cc1cccc(OCC)c1

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.39
BCHE P06276 4/20 0.36
C5AR1 P21730 1/20 0.36
ALDH1A1 P00352 1/20 0.36
HTT P42858 1/20 0.36
MEP1B Q16820 1/20 0.35
PPARG P37231 6/20 0.35
PPARA Q07869 6/20 0.35
BACE1 P56817 2/20 0.33
TSHR P16473 2/20 0.33
TLR7 Q9NYK1 1/20 0.33
CETP P11597 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL650072 0.91 C5AR1 (0.41) MAPTBCHEC5AR1ALDH1A1HTT
SCHEMBL648961 0.91 TLR7 (0.36) MAPTBCHEC5AR1ALDH1A1HTT
SCHEMBL649549 0.91 MAPT (0.45) MAPTBCHEC5AR1ALDH1A1PPARG
SCHEMBL1913030 0.91 TSHR (0.39) C5AR1ALDH1A1HTTPPARGPPARA
SCHEMBL649822 0.91 C5AR1 (0.39) MAPTBCHEC5AR1ALDH1A1HTT
SCHEMBL649888 0.90 C5AR1 (0.40) MAPTBCHEC5AR1ALDH1A1HTT
SCHEMBL647849 0.89 CRHR1 (0.38) MAPTBCHEC5AR1ALDH1A1HTT
SCHEMBL652368 0.88 C5AR1 (0.39) MAPTBCHEC5AR1ALDH1A1HTT
SCHEMBL650215 0.88 C5AR1 (0.38) MAPTBCHEC5AR1ALDH1A1HTT
SCHEMBL651651 0.88 C5AR1 (0.39) MAPTC5AR1ALDH1A1HTTBACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 131 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230348700-A1 FLAME-RETARDANT RESIN COMPOSITION, MANUFACTURING METHOD OF SAME, FLAME-RETARDANT RESIN MOLDED PRODUCT, AND FLAME-RETARDANT RESIN HOUSING Konica Minolta, Inc. (JP) 2023-11-02 US disclosed
WO-2023157910-A1 POLYCARBONATE-BASED RESIN COMPOSITION 出光興産株式会社 2023-08-24 WO disclosed
US-20230029379-A1 METHOD FOR PRODUCING AN OPTICAL ELEMENT FROM PLASTIC DOCTER OPTICS SE (DE) 2023-01-26 US disclosed
CN-110832029-B Polycarbonate resin composition and molded article thereof 出光兴产株式会社 2022-12-06 CN disclosed
WO-2022215657-A1 POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLES 出光興産株式会社 2022-10-13 WO disclosed
CN-110402270-B Flame-retardant polycarbonate resin composition and molded article thereof 出光兴产株式会社 2022-06-14 CN disclosed
CN-110366573-B Polycarbonate-polyorganosiloxane copolymer, polycarbonate resin composition containing same, and molded article thereof 出光兴产株式会社 2022-04-26 CN disclosed
CN-110352220-B Polycarbonate resin composition and molded article thereof 出光兴产株式会社 2022-04-01 CN disclosed
CN-110352210-B Polycarbonate-polyorganosiloxane copolymer, polycarbonate resin composition containing same, and molded article thereof 出光兴产株式会社 2022-03-25 CN disclosed
CN-110382624-B Polycarbonate resin composition and molded article thereof 出光兴产株式会社 2022-03-08 CN disclosed
US-5306801-A Heat resistance, hue stability, water resistance GE PLASTICS JAPAN, LTD. (JP) 1994-04-26 US disclosed
US-5276109-A Molding materials with transparency GENERAL ELECTRIC COMPANY (US) 1994-01-04 US disclosed
EP-0575810-A2 Polycarbonate and process for producing the same IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1993-12-29 EP disclosed
US-5254614-A With adipic or tartaric acid to prevent formation of defects under high temperature and humidity MITSUBISHI KASEI CORPORATION (JP) 1993-10-19 US disclosed
EP-0561638-A1 Optical-grade polycarbonate resin compositions GE PLASTICS JAPAN LIMITED (JP) 1993-09-22 EP disclosed
EP-0520806-A2 Optical polycarbonate compositions GE PLASTICS JAPAN LIMITED (JP) 1992-12-30 EP disclosed
EP-0520805-A2 Polycarbonate production method GE PLASTICS JAPAN LIMITED (JP) 1992-12-30 EP disclosed
EP-0520804-A2 Copolymeric polycarbonate production method GE PLASTICS JAPAN LIMITED (JP) 1992-12-30 EP disclosed
EP-0488182-A2 Process for producing a polycarbonate IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1992-06-03 EP disclosed
US-4429083-A Process for the production of polyesterpolycarbonate IDEMITSU KOSAN COMPANY LIMITED (JP) 1984-01-31 US disclosed