Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 7/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 7/20 | 0.45 |
| ▸ | PIK3C2B | O00750 | 3/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.39 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.38 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.38 |
| ▸ | MCTS1 | Q9ULC4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6501511 | 0.92 | BCL2 (0.38) | BCL2MCL1PIK3C2BALDH1A1DCTPP1 | |
| SCHEMBL7203763 | 0.90 | PIK3C2B (0.41) | BCL2MCL1PIK3C2BALDH1A1DCTPP1 | |
| SCHEMBL6489142 | 0.90 | GLP1R (0.42) | BCL2MCL1 | |
| SCHEMBL6500552 | 0.89 | MRGPRX4 (0.49) | BCL2MCL1PIK3C2BPLA2G2A | |
| SCHEMBL6501134 | 0.87 | BCL2 (0.47) | BCL2MCL1PIK3C2BPLA2G2A | |
| SCHEMBL6499333 | 0.87 | BCL2 (0.50) | BCL2MCL1PIK3C2BPLA2G2A | |
| SCHEMBL6492408 | 0.86 | BCL2 (0.48) | BCL2MCL1PIK3C2BPLA2G2A | |
| SCHEMBL6496934 | 0.85 | MCL1 (0.54) | BCL2MCL1PIK3C2BPLA2G2A | |
| SCHEMBL6488053 | 0.84 | BCL2 (0.43) | BCL2MCL1PIK3C2BPLA2G2A | |
| SCHEMBL6497244 | 0.84 | BCL2 (0.44) | BCL2MCL1PIK3C2BPLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | SLC5A1, SLC5A2, G6PD | BCL2 774/4885MCL1 806/4885PIK3C2B 2433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.