Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 4/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.50 |
| ▸ | FNTA | P49354 | 1/20 | 0.46 |
| ▸ | FNTB | P49356 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.46 |
| ▸ | DRD2 | P14416 | 3/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL651258 | 0.86 | FNTA (0.55) | FNTAFNTBALDH1A1HTTHDAC8 | |
| SCHEMBL652931 | 0.85 | FNTA (0.51) | FNTAFNTBALDH1A1TP53HTT | |
| SCHEMBL651390 | 0.85 | FNTA (0.49) | FNTAFNTBALDH1A1HTTHDAC8 | |
| SCHEMBL651621 | 0.84 | FNTA (0.50) | FNTAFNTBDRD2ALDH1A1HTT | |
| SCHEMBL652980 | 0.84 | FNTA (0.49) | FNTAFNTBALDH1A1HTTHDAC8 | |
| SCHEMBL651334 | 0.84 | FNTA (0.49) | FNTAFNTBDRD2ALDH1A1HTT | |
| SCHEMBL653026 | 0.83 | FNTA (0.49) | FNTAFNTBALDH1A1HTTHDAC8 | |
| SCHEMBL651205 | 0.83 | FNTA (0.48) | FNTAFNTBADRA1AADRA1BDRD2 | |
| SCHEMBL651292 | 0.82 | FNTA (0.48) | FNTAFNTBADRA1AADRA1BDRD2 | |
| SCHEMBL654001 | 0.82 | FNTA (0.47) | FNTAFNTBALDH1A1HTTHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7884113-B2 | Tetrahydroquinoline derivatives as cannabinoid receptor modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2011-02-08 | — | — | US | claimed |
| US-20080194625-A1 | TETRAHYDROQUINOLINE DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS | BRISTOL-MYERS SQUIBB COMPANY | 2008-08-14 | — | — | US | claimed |
| US-20050014786-A1 | Tetrahydroquinoline derivatives as cannabinoid receptor modulators | BRISTOL-MYERS SQUIBB COMPANY | 2005-01-20 | — | — | US | claimed |
| EP-0876369-A1 | 2- 2- (2-HYDROXYETHYL)AMINO]ETHYL]-5- 2-METHYLAMINO)ETHYL]AMINO]INDAZOLO 4,3-gh]ISOQUINOLIN-6(2H)-ONE AS ANTITUMOR AGENT | BOEHRINGER MANNHEIM ITALIA S.p.A. (IT) | 1998-11-11 | — | — | EP | claimed |
| WO-1997010245-A1 | 2-[2-[(2-HYDROXYETHYL)AMINO]ETHYL]-5-[[2-METHYLAMINO)ETHYL]AMINO]INDAZOLO[4,3-gh]ISOQUINOLIN-6(2H)-ONE AS ANTITUMOR AGENT | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1997-03-20 | — | — | WO | claimed |
| US-20230279312-A1 | PROCESSES FOR MAKING CONCENTRATED SURFACTANT BLENDS | THE PROCTER & GAMBLE COMPANY | 2023-09-07 | — | — | US | disclosed |
| WO-2022117575-A1 | PROCESS FOR THE CONVERSION OF ETHANE TO ETHYLENE GLYCOL | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2022-06-09 | — | — | WO | disclosed |
| EP-4008707-A1 | PROCESS FOR THE CONVERSION OF ETHANE TO ETHYLENE GLYCOL | Studiengesellschaft Kohle mbH (DE) | 2022-06-08 | — | — | EP | disclosed |
| CN-105612142-B | Esterification unit for producing crude methyl methacrylate, esterification method using the same | 阿肯马法国公司 | 2021-09-07 | — | — | CN | disclosed |
| US-11084774-B2 | Esterification unit for producing crude methyl methacrylate, esterification process using said unit and plant comprising said unit | TRINSEO EUROPE GMBH | 2021-08-10 | — | — | US | disclosed |
| WO-2021084330-A1 | FUNCTIONALIZED OLEFIN OLIGOMERS | CHEVRON ORONITE COMPANY LLC (US) | 2021-05-06 | — | — | WO | disclosed |
| US-20200270195-A1 | ESTERIFICATION UNIT FOR PRODUCING CRUDE METHYL METHACRYLATE, ESTERIFICATION PROCESS USING SAID UNIT AND PLANT COMPRISING SAID UNIT | ALTER DOMUS (US) LLC | 2020-08-27 | — | — | US | disclosed |
| US-5780421-A | Sulfated/sulfonated surfactants | HENKEL CORPORATION (US) | 1998-07-14 | — | — | US | disclosed |
| WO-1997032953-A1 | NOVEL SULFATED/SULFONATED SURFACTANTS | HENKEL CORPORATION (US) | 1997-09-12 | — | — | WO | disclosed |
| CN-1119866-A | Enantioselective synthesis of 5,6-dihydro-(S)-4-(ethylamino)-(S)-6-methyl-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide and related compounds | MERCK & CO INC (US) | 1996-04-03 | — | — | CN | disclosed |
| US-5288908-A | Process for the preparation of fluorine containing monomers | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-02-22 | — | — | US | disclosed |
| CN-1023118-C | Monomer containing fluorine, process for preparing them and use | HOECHST AG (DE) | 1993-12-15 | — | — | CN | disclosed |
| CN-1041358-A | Fluorochemical monomer, their preparation method and application thereof | HOECHST AG (DE) | 1990-04-18 | — | — | CN | disclosed |
| US-4782150-A | FIBER-REACTIVE DYES | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-11-01 | — | — | US | disclosed |
| US-4140685-A | BY NEUTRALIZATION WITH AMMONIA AND THEN EXTRACTION | STAMICARBON, B.V. (NL) | 1979-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11084774-B2 | Esterification unit for producing crude methyl methacrylate, esterification process using said unit and plant comprising said unit | MMAB, SAMM50, MRM1 | PDE4A 2672/4885PDE4B 2449/4885PDE4C 1969/4885 |
| US-20050014786-A1 | Tetrahydroquinoline derivatives as cannabinoid receptor modulators | CNR2, CNR1, OPRL1 | PDE4A 1688/4885PDE4B 1524/4885PDE4C 1727/4885 |
| US-20200270195-A1 | ESTERIFICATION UNIT FOR PRODUCING CRUDE METHYL METHACRYLATE, ESTERIFICATION PROCESS USING SAID UNIT AND PLANT COMPRISING SAID UNIT | MMAB, SAMM50, MRM1 | PDE4A 2672/4885PDE4B 2449/4885PDE4C 1969/4885 |
| US-20080194625-A1 | TETRAHYDROQUINOLINE DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS | CNR2, CNR1, OPRL1 | PDE4A 1688/4885PDE4B 1524/4885PDE4C 1727/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.