SCHEMBL650096

SCHEMBL650096

C/C=C/C(=O)OCC(O)CC

nearest known ligand 0.36

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 3/20 0.36
ATM Q13315 1/20 0.36
TSHR P16473 2/20 0.35
GSTP1 P09211 1/20 0.35
MAPT P10636 2/20 0.34
KDM4E B2RXH2 1/20 0.33
DUSP3 P51452 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
LMNA P02545 1/20 0.33
TDP1 Q9NUW8 1/20 0.32
USP2 O75604 1/20 0.32
ALDH1A1 P00352 1/20 0.32
CYP3A4 P08684 1/20 0.32
HPGD P15428 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL650097 1.00 HCAR2 (0.36) HCAR2ATMTSHRGSTP1MAPT
SCHEMBL20335453 0.90 TSHR (0.39) HCAR2ATMTSHRGSTP1MAPT
SCHEMBL8326024 0.90 HCAR2 (0.45) HCAR2ATMTSHRMAPTKDM4E
SCHEMBL6049909 0.90 HCAR2 (0.45) HCAR2ATMTSHRMAPTKDM4E
SCHEMBL11050380 0.90 HCAR2 (0.45) HCAR2ATMTSHRMAPTKDM4E
SCHEMBL9398191 0.87 LMNA (0.38) HCAR2ATMTSHRMAPTKDM4E
SCHEMBL9398188 0.87 LMNA (0.38) HCAR2ATMTSHRMAPTKDM4E
SCHEMBL23581952 0.84 TSHR (0.35) HCAR2ATMTSHRGSTP1MAPT
SCHEMBL347488 0.84 TSHR (0.35) HCAR2ATMTSHRGSTP1MAPT
SCHEMBL2868662 0.84 KDM4E (0.43) HCAR2ATMTSHRGSTP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104136519-B The tread mix containing microgel for Tire used in winter 阿朗新科德国有限责任公司 2018-03-02 CN disclosed
US-20150031790-A1 MICROGEL-CONTAINING TREAD MIXTURE FOR WINTER TYRES ARLANXEO DEUTSCHLAND GMBH (DE) 2015-01-29 US disclosed
US-20120108724-A1 STORAGE-STABLE, HYDROXY-MODIFIED MICROGEL LATICES LANXESS DEUTSCHLAND GMBH (DE) 2012-05-03 US disclosed
US-8119728-B2 Storage-stable, hydroxy-modified microgel latices LANXESS DEUTSCHLAND GMBH (DE) 2012-02-21 US disclosed
US-20100120973-A1 STORAGE-STABLE, HYDROXY-MODIFIED MICROGEL LATICES LANXESS DEUTSCHLAND GMBH (DE) 2010-05-13 US disclosed
US-4323363-A DISPERSE DYE USED ON POLYESTERS MIXED WITH CELLULOSE CASSELLA AKTIENGESELLSCHAFT (DE) 1982-04-06 US disclosed
US-4017448-A Transparent pigment dispersion process CELANESE COATINGS & SPECIALTIES COMPANY (US) 1977-04-12 US disclosed