Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 4/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6060873 | 0.84 | PPARA (0.51) | PPARAPPARGPPARD | |
| SCHEMBL6060870 | 0.84 | PPARA (0.51) | PPARAPPARGPPARD | |
| SCHEMBL5554858 | 0.83 | PPARA (0.42) | LMNAHTTSMN1; SMN2TMEM97SIGMAR1 | |
| SCHEMBL5553481 | 0.82 | PPARA (0.48) | ALDH1A1SMN1; SMN2TMEM97SIGMAR1POLB | |
| SCHEMBL5549733 | 0.82 | APEX1 (0.39) | HPGDALDH1A1SMN1; SMN2TMEM97SIGMAR1 | |
| SCHEMBL6498853 | 0.81 | PPARA (0.47) | LMNAPOLBTHRBRECQLTDP1 | |
| SCHEMBL6502863 | 0.81 | TMEM97 (0.47) | LMNAHTTGAAHPGDALDH1A1 | |
| SCHEMBL6494267 | 0.81 | PPARA (0.44) | LMNATMEM97SIGMAR1POLBTHRB | |
| SCHEMBL5554903 | 0.81 | PPARA (0.43) | LMNAHPGDALDH1A1POLBTHRB | |
| SCHEMBL5553504 | 0.80 | CTSL (0.40) | HPGDALDH1A1SMN1; SMN2TMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |