Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5492205 | 0.64 | KDM4E (0.33) | ALDH1A1HPGDHSD17B10 | |
| SCHEMBL2230323 | 0.61 | ALDH1A1 (0.30) | ALDH1A1HPGDHSD17B10 | |
| SCHEMBL10517014 | 0.58 | — | — | |
| SCHEMBL18663893 | 0.57 | — | — | |
| SCHEMBL544039 | 0.55 | ALDH1A1 (0.58) | ALDH1A1HPGDHSD17B10 | |
| Pyridine SCHEMBL11383419 | 0.55 | — | — | |
| SCHEMBL134246 | 0.54 | — | — | |
| Pentane SCHEMBL28765480 | 0.54 | ALDH1A1 (0.33) | ALDH1A1HPGDHSD17B10 | |
| SCHEMBL10656161 | 0.54 | ALDH1A1 (0.32) | ALDH1A1HPGDHSD17B10 | |
| SCHEMBL10426159 | 0.54 | KDM4E (0.34) | ALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6897308-B1 | Process for the preparation of anti-psychotic 3-[2-[-4-(6-fluoro-1,2-benziosoxazol-3-yl)-1-piperidinyl] ethyl]-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one | RGP LIFE SCIENCES LIMITED (IN) | 2005-05-24 | — | — | US | claimed |