Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 14/20 | 1.00 |
| ▸ | ADORA3 | P0DMS8 | 8/20 | 0.71 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.71 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26053899 | 0.84 | ADORA1 (0.72) | ADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL6505603 | 0.83 | ADORA1 (1.00) | ADORA1ADORA3ADORA2AADORA2BKDM4E | |
| SCHEMBL26053924 | 0.83 | ADORA1 (0.71) | ADORA1ADORA3ADORA2AADORA2BSMN1; SMN2 | |
| SCHEMBL16391805 | 0.82 | ADORA1 (0.72) | ADORA1ADORA3ADORA2AADORA2BSMN1; SMN2 | |
| SCHEMBL4829224 | 0.82 | ADORA1 (1.00) | ADORA1ADORA3ADORA2AADORA2BSMN1; SMN2 | |
| SCHEMBL6499771 | 0.81 | ADORA1 (1.00) | ADORA1ADORA3ADORA2AADORA2BKDM4E | |
| SCHEMBL24227646 | 0.80 | ADORA1 (0.72) | ADORA1ADORA3ADORA2AADORA2BMAPT | |
| SCHEMBL6502989 | 0.80 | ADORA1 (1.00) | ADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL24227492 | 0.79 | ADORA1 (0.76) | ADORA1ADORA3ADORA2AADORA2BKDM4E | |
| SCHEMBL26055757 | 0.78 | ADORA1 (1.00) | ADORA1ADORA3ADORA2AADORA2BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005033085-A1 | PYRIMIDINES DERIVATIVES AS ADENOSINE RECEPTORS LIGANDS | UNIVERSITEIT LEIDEN (NL) | 2005-04-14 | — | — | WO | claimed |
| WO-2005033085-A1 | PYRIMIDINES DERIVATIVES AS ADENOSINE RECEPTORS LIGANDS | UNIVERSITEIT LEIDEN (NL) | 2005-04-14 | — | — | WO | disclosed |