Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 17/20 | 1.00 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.69 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.67 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.63 |
| ▸ | NOS1 | P29475 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19699609 | 0.84 | ADORA1 (0.73) | ADORA1ADORA3ADORA2ANOS1 | |
| SCHEMBL6497567 | 0.83 | ADORA1 (1.00) | ADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL26053899 | 0.82 | ADORA1 (0.72) | ADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL26055757 | 0.81 | ADORA1 (1.00) | ADORA1ADORA3ADORA2AADORA2BTDP1 | |
| SCHEMBL6529699 | 0.81 | ADORA1 (0.74) | ADORA1ADORA3ADORA2AADORA2BTDP1 | |
| SCHEMBL16391790 | 0.81 | ADORA1 (0.70) | ADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL4822464 | 0.80 | ADORA1 (1.00) | ADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL6501467 | 0.80 | ADORA1 (1.00) | ADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL26053924 | 0.78 | ADORA1 (0.71) | ADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL6507291 | 0.77 | ADORA1 (1.00) | ADORA1ADORA3ADORA2AADORA2BTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005033085-A1 | PYRIMIDINES DERIVATIVES AS ADENOSINE RECEPTORS LIGANDS | UNIVERSITEIT LEIDEN (NL) | 2005-04-14 | — | — | WO | claimed |
| US-20230271983-A1 | FUNCTIONALIZED ISONITRILES AND PRODUCTS, PREPARATION AND USES THEREOF | UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) | 2023-08-31 | — | — | US | disclosed |
| US-20230271983-A1 | FUNCTIONALIZED ISONITRILES AND PRODUCTS, PREPARATION AND USES THEREOF | UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) | 2023-08-31 | — | — | US | disclosed |
| US-20050272740-A1 | Benzimidazole derivatives | MERCK PATENT GMBH (DE) | 2005-12-08 | — | — | US | disclosed |
| WO-2005033085-A1 | PYRIMIDINES DERIVATIVES AS ADENOSINE RECEPTORS LIGANDS | UNIVERSITEIT LEIDEN (NL) | 2005-04-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050272740-A1 | Benzimidazole derivatives | F12, F11, SERPINC1 | ADORA1 572/4885ADORA3 778/4885ADORA2A 2033/4885 |
| US-20230271983-A1 | FUNCTIONALIZED ISONITRILES AND PRODUCTS, PREPARATION AND USES THEREOF | KIT, MACF1, IK | ADORA1 1360/4885ADORA3 1458/4885ADORA2A 2807/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.