Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | SCN5A | Q14524 | 11/20 | 0.48 |
| ▸ | SCN8A | Q9UQD0 | 5/20 | 0.48 |
| ▸ | SCN1A | P35498 | 4/20 | 0.48 |
| ▸ | SCN9A | Q15858 | 14/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | PPIA | P62937 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16757049 | 0.72 | SCN9A (0.80) | SCN5ASCN8ASCN9ACYP3A4NR1I2 | |
| SCHEMBL20096109 | 0.72 | SCN5A (0.62) | SCN5ASCN8ASCN1A | |
| SCHEMBL16757048 | 0.71 | SCN9A (0.60) | SCN5ASCN9ACYP3A4 | |
| SCHEMBL31566916 | 0.70 | SCN8A (0.59) | SCN8ASCN1ASCN9A | |
| SCHEMBL31566467 | 0.70 | SCN8A (0.59) | SCN8ASCN1ASCN9A | |
| SCHEMBL17545149 | 0.70 | USP2 (0.53) | USP2MAPTESR2HSD17B10SCN5A | |
| SCHEMBL20115734 | 0.70 | SCN9A (0.56) | SCN8ASCN9ACYP3A4 | |
| SCHEMBL19219769 | 0.70 | USP2 (0.49) | USP2MAPTESR2HSD17B10SCN5A | |
| SCHEMBL30479336 | 0.69 | SCN9A (0.58) | SCN5ASCN8ASCN1ASCN9ACYP3A4 | |
| SCHEMBL20115795 | 0.69 | SCN9A (0.58) | SCN5ASCN8ASCN1ASCN9ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014591-A1 | 2-ACYLAMINO OR 2-SULFONYLAMINO-1, 3-THIAZOLES AS COUPLERS FOR THE OXIDATION DYEING OF KERATIN FIBRES | L'OREAL (FR) | 2005-02-17 | — | — | WO | disclosed |