Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CCR1 | P32246 | 1/20 | 0.45 |
| ▸ | CCR2 | P41597 | 1/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13603832 | 0.83 | SMN1; SMN2 (0.46) | NOTUMMAPTKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8104378 | 0.83 | SMN1; SMN2 (0.46) | NOTUMMAPTKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL3448024 | 0.83 | HPGD (0.43) | MAPTHPGDTP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL27379472 | 0.81 | ALOX5 (0.44) | MAPTSMN1; SMN2HSD11B1 | |
| SCHEMBL14632375 | 0.80 | NOTUM (0.56) | NOTUMKMT2AHSD11B1 | |
| SCHEMBL6839819 | 0.80 | NOTUM (0.56) | NOTUMKMT2AHSD11B1 | |
| SCHEMBL11985481 | 0.79 | KMT2A (0.52) | MAPTKMT2AFFAR4FFAR1SMN1; SMN2 | |
| SCHEMBL1155903 | 0.79 | KMT2A (0.52) | MAPTKMT2AFFAR4FFAR1SMN1; SMN2 | |
| SCHEMBL10311098 | 0.79 | ALOX5 (0.47) | MAPTKMT2AHPGDALDH1A1HSD11B1 | |
| SCHEMBL14632437 | 0.79 | F10 (0.53) | KMT2AHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005019200-A2 | ARYL PIPERIDINE DERIVATIVES AS VLA-1 INTEGRIN ANTAGONISTS AND USES THEREOF | ICOS CORPORATION (US) | 2005-03-03 | — | — | WO | disclosed |