Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.47 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 7/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.39 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.39 |
| ▸ | TNNC1 | P63316 | 5/20 | 0.39 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | GPR183 | P32249 | 1/20 | 0.39 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6507477 | 0.89 | S1PR1 (0.50) | CYP11B1CYP11B2CYP19A1SLC13A5S1PR1 | |
| Hydrochloric Acid SCHEMBL6529171 | 0.88 | S1PR1 (0.50) | SLC13A5S1PR1S1PR3TNNC1SGPL1 | |
| SCHEMBL6507059 | 0.82 | S1PR1 (0.51) | CYP19A1SLC13A5S1PR1S1PR3TNNC1 | |
| SCHEMBL6508458 | 0.82 | S1PR1 (0.59) | S1PR1S1PR3TNNC1SGPL1S1PR4 | |
| SCHEMBL6504336 | 0.80 | S1PR1 (0.57) | S1PR1S1PR3TNNC1SGPL1S1PR4 | |
| SCHEMBL6502451 | 0.79 | S1PR1 (0.45) | FFAR1S1PR1S1PR3 | |
| SCHEMBL6502428 | 0.77 | FFAR1 (0.44) | CYP11B1CYP11B2CYP19A1FFAR1PPARD | |
| SCHEMBL6528364 | 0.76 | S1PR1 (0.61) | SLC13A5S1PR1S1PR3TNNC1SGPL1 | |
| Hydrochloric Acid SCHEMBL6526756 | 0.75 | S1PR1 (0.60) | SLC13A5S1PR1S1PR3TNNC1SGPL1 | |
| SCHEMBL6502535 | 0.75 | S1PR1 (0.63) | S1PR1S1PR3TNNC1SGPL1S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014525-A2 | BI-ARYL COMPOUND HAVING IMMUNOSUPPRESSIVE ACTIVITY | MITSUBISHI PHARMA CORPORATION (JP) | 2005-02-17 | — | — | WO | claimed |
| WO-2005014525-A2 | BI-ARYL COMPOUND HAVING IMMUNOSUPPRESSIVE ACTIVITY | MITSUBISHI PHARMA CORPORATION (JP) | 2005-02-17 | — | — | WO | disclosed |