Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 14/20 | 0.50 |
| ▸ | TNNC1 | P63316 | 5/20 | 0.48 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.48 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.48 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.48 |
| ▸ | GPR183 | P32249 | 1/20 | 0.48 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.48 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.48 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6529171 | 0.99 | S1PR1 (0.50) | S1PR1TNNC1S1PR3SGPL1S1PR4 | |
| SCHEMBL6502525 | 0.89 | CYP11B1 (0.47) | S1PR1TNNC1S1PR3SGPL1S1PR4 | |
| SCHEMBL3507784 | 0.80 | S1PR1 (0.55) | S1PR1TNNC1S1PR3SGPL1S1PR4 | |
| SCHEMBL6528364 | 0.79 | S1PR1 (0.61) | S1PR1TNNC1S1PR3SGPL1S1PR4 | |
| Hydrochloric Acid SCHEMBL6526756 | 0.78 | S1PR1 (0.60) | S1PR1TNNC1S1PR3SGPL1S1PR4 | |
| SCHEMBL3742046 | 0.77 | S1PR1 (0.61) | S1PR1TNNC1S1PR3SGPL1S1PR4 | |
| SCHEMBL6528287 | 0.76 | S1PR1 (0.68) | S1PR1TNNC1S1PR3SGPL1S1PR4 | |
| SCHEMBL6530114 | 0.76 | SLC13A5 (0.45) | S1PR1SLC13A5CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL19910990 | 0.75 | CYP11B1 (0.63) | CYP19A1CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL6528090 | 0.74 | S1PR1 (0.69) | S1PR1TNNC1S1PR3SGPL1S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014525-A2 | BI-ARYL COMPOUND HAVING IMMUNOSUPPRESSIVE ACTIVITY | MITSUBISHI PHARMA CORPORATION (JP) | 2005-02-17 | — | — | WO | claimed |
| WO-2005051380-A1 | SUBSTITUTED UREA-OCTAHYDROINDOLS AS ANTAGONISTS OF MELANIN CONCENTRATING HORMONE RECEPTOR 1 (MCH1R) | BIOVITRUM AB (SE) | 2005-06-09 | — | — | WO | disclosed |
| WO-2005014525-A2 | BI-ARYL COMPOUND HAVING IMMUNOSUPPRESSIVE ACTIVITY | MITSUBISHI PHARMA CORPORATION (JP) | 2005-02-17 | — | — | WO | disclosed |