Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL6502964

CN(Cc1nccn1-c1ccc2c(c1)CCN2C(=O)c1cc(C(N)=O)nn1-c1ccc2onc(N)c2c1)S(C)(=O)=O.O=C(O)C(F)(F)F

nearest known ligand 0.92

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.92
F2 P00734 3/20 0.52
F9 P00740 1/20 0.48
F5 P12259 1/20 0.48
CTRB1 P17538 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6494926 0.96 F10 (1.00) F10F2F9F5CTRB1
Trifluoroacetic Acid SCHEMBL6495496 0.92 F10 (0.91) F10F2F9F5CTRB1
SCHEMBL6494300 0.87 F10 (1.00) F10F2F9F5CTRB1
SCHEMBL6609040 0.83 F10 (0.81) F10F2F9F5CTRB1
Trifluoroacetic Acid SCHEMBL6105097 0.81 F10 (0.91) F10F2
SCHEMBL6504393 0.80 F10 (0.70) F10F2F9F5CTRB1
SCHEMBL1999386 0.78 F10 (1.00) F10F2
Trifluoroacetic Acid SCHEMBL6109136 0.77 F10 (0.91) F10F2
SCHEMBL6107432 0.76 F10 (1.00) F10F2
Trifluoroacetic Acid SCHEMBL2001149 0.75 F10 (0.89) F10F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6949550-B2 Substituted amino methyl factor Xa inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2005-09-27 US disclosed
US-20030212054-A1 Substituted amino methyl factor Xa inhibitors BRISTOL-MYERS SQUIBB COMPANY 2003-11-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030212054-A1 Substituted amino methyl factor Xa inhibitors F11, F10, F9 F10 2/4885F2 12/4885F9 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.