Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIP5K1C | O60331 | 19/20 | 0.79 |
| ▸ | PIK3CA | P42336 | 16/20 | 0.79 |
| ▸ | PIP5K1B | O14986 | 3/20 | 0.71 |
| ▸ | PIP5K1A | Q99755 | 3/20 | 0.71 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.71 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.71 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.71 |
| ▸ | PI4KA | P42356 | 2/20 | 0.71 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.71 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.71 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.71 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.68 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.68 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6504296 | 0.92 | PIP5K1C (0.79) | PIP5K1CPIK3CAPIP5K1BPIP5K1APIK3CD | |
| SCHEMBL6530015 | 0.91 | PIP5K1C (0.85) | PIP5K1CPIK3CAPIP5K1BPIP5K1APIK3CD | |
| SCHEMBL6504937 | 0.90 | PIP5K1C (0.77) | PIP5K1CPIK3CAPIP5K1BPIP5K1APIK3CD | |
| SCHEMBL6510087 | 0.90 | PIP5K1C (0.85) | PIP5K1CPIK3CAPIP5K1BPIP5K1APIK3CD | |
| SCHEMBL6501794 | 0.90 | PIP5K1C (0.73) | PIP5K1CPIK3CAPIP5K1BPIP5K1APIK3CD | |
| SCHEMBL6507850 | 0.89 | PIP5K1C (0.84) | PIP5K1CPIK3CAPIP5K1BPIP5K1APIK3CD | |
| SCHEMBL6533225 | 0.89 | PIP5K1C (0.74) | PIP5K1CPIK3CAPIP5K1BPIP5K1APIK3CD | |
| SCHEMBL6501419 | 0.88 | PIP5K1C (1.00) | PIP5K1CPIK3CAPIP5K1BPIP5K1APIK3CD | |
| SCHEMBL6502234 | 0.88 | PIP5K1C (0.83) | PIP5K1CPIK3CAPIP5K1BPIP5K1APIK3CD | |
| SCHEMBL6531186 | 0.88 | PIP5K1C (0.70) | PIP5K1CPIK3CAPIP5K1BPIP5K1APIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005051381-A1 | Substituted urea-octatydroindols as antagonists of melanin concentrating hormone receptor 1 (MCH1R) | BIOVITRUM AB (SE) | 2005-06-09 | — | — | WO | claimed |
| WO-2005003123-A1 | NOVEL PYRIDINE DERIVATIVES AS JNK SPECIFIC INHIBITORS | ASTRAZENECA AB (SE) | 2005-01-13 | — | — | WO | claimed |
| WO-2005003123-A1 | NOVEL PYRIDINE DERIVATIVES AS JNK SPECIFIC INHIBITORS | ASTRAZENECA AB (SE) | 2005-01-13 | — | — | WO | disclosed |