Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.49 |
| ▸ | ACACA | Q13085 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6481434 | 0.88 | LMNA (0.49) | ACACBACACAKMT2ALMNAALDH1A1 | |
| SCHEMBL6479149 | 0.88 | KMT2A (0.49) | ACACBACACAKMT2ALMNAALDH1A1 | |
| SCHEMBL6479667 | 0.87 | KMT2A (0.48) | ACACBACACAKMT2ALMNAALDH1A1 | |
| Dimethylamine SCHEMBL6533378 | 0.86 | KMT2A (0.48) | ACACBACACAKMT2ALMNAALDH1A1 | |
| SCHEMBL18854912 | 0.84 | KMT2A (0.66) | KMT2ALMNAALDH1A1KDM4EGAA | |
| SCHEMBL6480776 | 0.82 | KMT2A (0.53) | ACACBACACAKMT2ALMNAALDH1A1 | |
| SCHEMBL6491894 | 0.82 | KMT2A (0.52) | ACACBACACAKMT2ALMNAALDH1A1 | |
| SCHEMBL6491981 | 0.81 | KMT2A (0.51) | ACACBACACAKMT2ALMNAALDH1A1 | |
| SCHEMBL6481517 | 0.81 | KMT2A (0.53) | ACACBACACAKMT2ALMNAALDH1A1 | |
| SCHEMBL6492275 | 0.79 | ACACB (0.58) | ACACBACACAKMT2ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005007643-A1 | NOVEL ACRIDINE DERIVATIVES AND USE THEREOF AS MEDICAMENTS | ZENTARIS GMBH (DE) | 2005-01-27 | — | — | WO | disclosed |