⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL620462 | 0.71 | — | — | |
| SCHEMBL31563734 | 0.58 | ALDH1A1 (0.33) | — | |
| SCHEMBL8764127 | 0.55 | ALDH1A1 (0.32) | — | |
| SCHEMBL8762363 | 0.54 | — | — | |
| SCHEMBL17261552 | 0.54 | — | — | |
| SCHEMBL8763359 | 0.54 | ALDH1A1 (0.38) | — | |
| SCHEMBL17289572 | 0.54 | — | — | |
| SCHEMBL330601 | 0.54 | — | — | |
| SCHEMBL22265274 | 0.54 | — | — | |
| Ethylene Glycol SCHEMBL27861985 | 0.54 | MIF (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 185 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240218018-A1 | Compstatin Analogs with Increased Solubility and Improved Pharmacokinetic Properties | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2024-07-04 | — | — | US | disclosed |
| US-11884747-B2 | Compstatin analogs with increased solubility and improved pharmacokinetic properties | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2024-01-30 | — | — | US | disclosed |
| WO-2023178239-A1 | HPSC-DERIVED ARTICULAR CHONDROCYTE COMPOSITIONS, SYSTEMS AND METHODS OF USE THEREOF | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2023-09-21 | — | — | WO | disclosed |
| EP-4011905-A2 | COMPSTATIN ANALOGS WITH INCREASED SOLUBILITY AND IMPROVED PHARMACOKINETIC PROPERTIES | The Trustees Of The University Of Pennsylvania (US) | 2022-06-15 | — | — | EP | disclosed |
| CN-105582523-B | Compstatin and analogs thereof for ocular disorders | 阿佩利斯制药公司 | 2022-04-15 | — | — | CN | disclosed |
| EP-3645550-B1 | COMPSTATIN ANALOGS WITH INCREASED SOLUBILITY AND IMPROVED PHARMACOKINETIC PROPERTIES | UNIV PENNSYLVANIA (US) | 2021-11-03 | — | — | EP | disclosed |
| US-11078461-B2 | Compositions and methods for implantation of processed adipose tissue and processed adipose tissue products | THE JOHNS HOPKINS UNIVERSITY (US) | 2021-08-03 | — | — | US | disclosed |
| CN-112334477-A | Compstatin analogs with increased solubility and improved pharmacokinetic properties | 宾夕法尼亚大学理事会 | 2021-02-05 | — | — | CN | disclosed |
| US-10800812-B2 | Compstatin analogs with increased solubility and improved pharmacokinetic properties | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2020-10-13 | — | — | US | disclosed |
| US-20200188459-A1 | PROCESS FOR PREPARING METABOLIZED CONDITIONED GROWTH MEDIA | ALLERGAN INC (US) | 2020-06-18 | — | — | US | disclosed |
| WO-2001055212-A2 | DELIVERY OF THERAPEUTIC BIOLOGICAL FROM IMPLANTABLE TISSUE MATRICES | THE GENERAL HOSPITAL CORPORATION (US) | 2001-08-02 | — | — | WO | disclosed |
| US-6224893-B1 | WOUND HEALING AGENT | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2001-05-01 | — | — | US | disclosed |
| WO-2000069449-A2 | CONDITIONED CELL CULTURE MEDIUM COMPOSITIONS AND METHODS OF USE | ADVANCED TISSUE SCIENCES, INC. (US) | 2000-11-23 | — | — | WO | disclosed |
| US-6129761-A | Injectable hydrogel compositions | REPROGENESIS, INC. (US) | 2000-10-10 | — | — | US | disclosed |
| US-6096303-A | Method to enhance treatment of cystic tumors | MEDICAL COLLEGE OF GEORGIA RESEARCH INSTITUTE, INC. (US) | 2000-08-01 | — | — | US | disclosed |
| EP-1011633-A1 | SEMI-INTERPENETRATING OR INTERPENETRATING POLYMER NETWORKS FOR DRUG DELIVERY AND TISSUE ENGINEERING | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2000-06-28 | — | — | EP | disclosed |
| EP-0938343-A2 | TUMOR DELIVERY VEHICLES AND METHOD TO ENHANCE TREATMENT OF CYSTIC TUMORS | FBP Corporation (US) | 1999-09-01 | — | — | EP | disclosed |
| US-5945100-A | Tumor delivery vehicles | FBP CORPORATION (US) | 1999-08-31 | — | — | US | disclosed |
| WO-1998052543-A1 | SEMI-INTERPENETRATING OR INTERPENETRATING POLYMER NETWORKS FOR DRUG DELIVERY AND TISSUE ENGINEERING | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1998-11-26 | — | — | WO | disclosed |
| WO-1998004242-A2 | TUMOR DELIVERY VEHICLES AND METHOD TO ENHANCE TREATMENT OF CYSTIC TUMORS | FBP CORPORATION (US) | 1998-02-05 | — | — | WO | disclosed |