SCHEMBL650369

SCHEMBL650369

[SiH3]CC(c1ccccc1)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 6/20 0.52
TAAR1 Q96RJ0 1/20 0.52
HRH1 P35367 5/20 0.48
TDP1 Q9NUW8 1/20 0.44
DPP4 P27487 2/20 0.43
F2 P00734 1/20 0.43
TSHR P16473 1/20 0.43
CHRNB2 P17787 1/20 0.42
CHRNA4 P43681 1/20 0.42
MTOR P42345 1/20 0.42
RAB9A P51151 1/20 0.42
GRM7 Q14831 1/20 0.42
LMNA P02545 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18510289 0.79 TAAR1 (0.43) HTR2ATAAR1HRH1DPP4F2
SCHEMBL863751 0.77 HRH1 (0.56) HTR2ATAAR1HRH1TDP1LMNA
SCHEMBL8715487 0.75 TAAR1 (0.58) HTR2ATAAR1HRH1LMNA
SCHEMBL9838705 0.73 HTR2A (0.58) HTR2ATAAR1HRH1TDP1DPP4
SCHEMBL3290730 0.73 HRH1 (0.68) HTR2ATAAR1HRH1TDP1DPP4
SCHEMBL3104687 0.73 HTR2A (0.50) HTR2ATAAR1HRH1TDP1DPP4
Lithium Ion SCHEMBL3114909 0.73 HTR2A (0.50) HTR2ATAAR1HRH1TDP1DPP4
Potassium Ion SCHEMBL3116529 0.73 HTR2A (0.50) HTR2ATAAR1HRH1TDP1DPP4
SCHEMBL381286 0.73 HRH1 (0.60) HTR2ATAAR1HRH1LMNA
SCHEMBL844862 0.71 HRH1 (0.65) HTR2ATAAR1HRH1TDP1DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 512 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3998304-A2 ORGANIC SEMICONDUCTOR COMPOSITIONS SmartKem Limited (GB) 2022-05-18 EP claimed
EP-2817355-B1 ORGANIC SEMICONDUCTOR COMPOSITIONS SMARTKEM LTD (GB) 2021-03-24 EP claimed
EP-2817356-B1 ORGANIC SEMICONDUCTOR COMPOSITIONS SMARTKEM LTD (GB) 2021-02-17 EP claimed
EP-2817354-B1 ORGANIC SEMICONDUCTOR COMPOSITIONS SMARTKEM LTD (GB) 2021-01-13 EP claimed
EP-2817357-B1 ORGANIC SEMICONDUCTOR COMPOSITIONS SMARTKEM LTD (GB) 2020-11-04 EP claimed
EP-2817351-B1 ORGANIC SEMICONDUCTOR COMPOSITIONS SMARTKEM LTD (GB) 2020-08-26 EP claimed
EP-2817352-B1 ORGANIC SEMICONDUCTOR COMPOSITIONS SMARTKEM LTD (GB) 2020-08-26 EP claimed
US-10707420-B2 Polycyclic aromatic hydrocarbon copolymer-containing organic semiconductor compositions SMARTKEM LIMITED (GB) 2020-07-07 US claimed
US-10056551-B2 Polycyclic aromatic hydrocarbon polymers and their use as organic semiconductors SMARTKEM LIMITED (GB) 2018-08-21 US claimed
US-10056550-B2 Polycyclic aromatic hydrocarbon copolymers and their use as organic semiconductors SMARTKEM LIMITED (GB) 2018-08-21 US claimed
WO-2013124685-A1 ORGANIC SEMICONDUCTOR COMPOSITIONS SMARTKEM LIMITED (GB) 2013-08-29 WO claimed
WO-2013124686-A1 ORGANIC SEMICONDUCTOR COMPOSITIONS SMARTKEM LIMITED (GB) 2013-08-29 WO claimed
WO-2013124684-A1 ORGANIC SEMICONDUCTOR COMPOSITIONS SMARTKEM LIMITED (GB) 2013-08-29 WO claimed
WO-2013124688-A2 ORGANIC SEMICONDUCTOR COMPOSITIONS SMARTKEM LIMITED (GB) 2013-08-29 WO claimed
US-20100137525-A1 Catalyst composition for hydrogenation and their use for hydrogenation conjugated diene polymer CHI-MEI CORPORATION 2010-06-03 US claimed
US-20080171653-A1 Catalyst composition for hydrogenation and their use for hydrogenation conjugated diene polymer CHI-MEI CORPORATION 2008-07-17 US claimed
CN-1130382-C Catalyst composition for hydrogenation of conjugated diene polymer and process for hydrogenation of the polymer INST IND TECHNOLOGY (CN) 2003-12-10 CN claimed
CN-1324867-A Catalyst composition for hydrogenation of conjugated diene polymer and process for hydrogenation of the polymer INST OF IND TECHN (CN) 2001-12-05 CN claimed
US-6313230-B1 HYDROGENATING CONJUGATED DIENE POLYMERS IN PRESENCE OF HYDROGEN AND A HYDROGENATION CATALYST FORMULATION COMPRISING TITANIUM COMPOUND, SILYL HYDRIDE COMPOUND, POLYSILOXANE, SILAZAN COMPOUND, AND METALLIC COMPOUND INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2001-11-06 US claimed
US-5354340-A Preparation of copolymers SHELL OIL COMPANY (US) 1994-10-11 US claimed