Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.44 |
| ▸ | PNMT | P11086 | 2/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.39 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 5/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1694942 | 0.83 | PNMT (0.46) | TAAR1PNMTHTR3EHTR3BHTR3A | |
| SCHEMBL3786637 | 0.79 | TAAR1 (0.44) | TAAR1PNMTIDO1SLC6A2SLC6A4 | |
| SCHEMBL29924786 | 0.78 | TAAR1 (0.63) | TAAR1PNMTIDO1TSHR | |
| SCHEMBL992770 | 0.78 | CD44 (0.39) | TAAR1IDO1TSHRSLC6A2SLC6A4 | |
| SCHEMBL2963562 | 0.78 | TAAR1 (0.63) | TAAR1PNMTIDO1TSHR | |
| SCHEMBL30645118 | 0.78 | CD44 (0.39) | TAAR1IDO1TSHRSLC6A2SLC6A4 | |
| SCHEMBL10624720 | 0.78 | TAAR1 (0.45) | TAAR1IDO1TSHR | |
| SCHEMBL3675893 | 0.78 | PNMT (0.50) | TAAR1PNMTIDO1TSHR | |
| SCHEMBL29538519 | 0.78 | TAAR1 (0.60) | TAAR1PNMTHTR3EHTR3BHTR3A | |
| SCHEMBL624730 | 0.78 | TAAR1 (0.60) | TAAR1PNMTHTR3EHTR3BHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005082885-A1 | IMIDAZOLE BASED KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-09-09 | — | — | WO | disclosed |