Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 15/20 | 0.47 |
| ▸ | PPARD | Q03181 | 11/20 | 0.47 |
| ▸ | PPARG | P37231 | 8/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6504500 | 0.91 | PPARA (0.53) | PPARAPPARDPPARGTSHRRECQL | |
| SCHEMBL6060873 | 0.90 | PPARA (0.51) | PPARAPPARDPPARG | |
| SCHEMBL6060870 | 0.90 | PPARA (0.51) | PPARAPPARDPPARG | |
| SCHEMBL6496475 | 0.88 | PPARA (0.46) | PPARAPPARDPPARGLMNA | |
| SCHEMBL6498853 | 0.85 | PPARA (0.47) | PPARAPPARDPPARGRECQLLMNA | |
| SCHEMBL6493753 | 0.84 | PPARA (0.58) | PPARAPPARDPPARG | |
| SCHEMBL6504240 | 0.83 | PPARA (0.52) | PPARAPPARDPPARG | |
| SCHEMBL6495864 | 0.83 | PPARA (0.53) | PPARAPPARDPPARG | |
| SCHEMBL6502968 | 0.83 | PPARA (0.46) | PPARAPPARDPPARGLMNA | |
| SCHEMBL6494267 | 0.83 | PPARA (0.44) | PPARAPPARDPPARGRECQLLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |