Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 17/20 | 0.53 |
| ▸ | PPARD | Q03181 | 14/20 | 0.53 |
| ▸ | PPARG | P37231 | 10/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6503847 | 0.91 | PPARA (0.47) | PPARAPPARDPPARGTSHRRECQL | |
| SCHEMBL6496012 | 0.90 | PPARA (0.57) | PPARAPPARDPPARG | |
| SCHEMBL6496351 | 0.89 | PPARA (0.51) | PPARAPPARDPPARG | |
| SCHEMBL6502380 | 0.88 | PPARA (0.69) | PPARAPPARDPPARG | |
| SCHEMBL6504240 | 0.82 | PPARA (0.52) | PPARAPPARDPPARG | |
| SCHEMBL6505998 | 0.82 | PPARA (0.58) | PPARAPPARDPPARG | |
| SCHEMBL6495864 | 0.82 | PPARA (0.53) | PPARAPPARDPPARG | |
| SCHEMBL6502968 | 0.82 | PPARA (0.46) | PPARAPPARDPPARG | |
| SCHEMBL6060873 | 0.81 | PPARA (0.51) | PPARAPPARDPPARG | |
| SCHEMBL6060870 | 0.81 | PPARA (0.51) | PPARAPPARDPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6936603-B2 | Substituted pyrazoles | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2005-08-30 | — | — | US | disclosed |
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| US-20030225062-A1 | Substituted pyrazoles | ORTHO MCNEIL PHARMACEUTICAL, INC. | 2003-12-04 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030225062-A1 | Substituted pyrazoles | CTSS, CTSZ, CTSV | PPARA 1683/4885PPARD 1204/4885PPARG 1159/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.