Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD4 | Q53EL6 | 4/20 | 0.37 |
| ▸ | DNTT | P04053 | 2/20 | 0.34 |
| ▸ | GLS2 | Q9UI32 | 2/20 | 0.34 |
| ▸ | TOP1 | P11387 | 3/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | POLA1 | P09884 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 2/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | PRKCG | P05129 | 1/20 | 0.33 |
| ▸ | PRKCB | P05771 | 1/20 | 0.33 |
| ▸ | PRKCH | P24723 | 1/20 | 0.33 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.33 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.33 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6505924 | 0.86 | PDCD4 (0.39) | PDCD4DNTTGLS2TOP1POLB | |
| SCHEMBL29970207 | 0.86 | PDCD4 (0.39) | PDCD4DNTTGLS2TOP1POLB | |
| SCHEMBL6505925 | 0.86 | PDCD4 (0.39) | PDCD4DNTTGLS2TOP1POLB | |
| SCHEMBL6527430 | 0.83 | PDCD4 (0.36) | PDCD4DNTTGLS2TOP1TRPA1 | |
| SCHEMBL30375807 | 0.79 | PDCD4 (0.40) | PDCD4DNTTTOP1TRPA1NR4A2 | |
| SCHEMBL18191881 | 0.79 | PDCD4 (0.40) | PDCD4DNTTTOP1TRPA1NR4A2 | |
| SCHEMBL6528440 | 0.74 | DNTT (0.36) | DNTTPOLBPOLA1PRKCAPRKD3 | |
| SCHEMBL6528441 | 0.74 | DNTT (0.36) | DNTTPOLBPOLA1PRKCAPRKD3 | |
| SCHEMBL6528438 | 0.74 | DNTT (0.36) | DNTTPOLBPOLA1PRKCAPRKD3 | |
| SCHEMBL6528851 | 0.73 | PDCD4 (0.42) | PDCD4DNTTGLS2TOP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005080311-A1 | HYGROPHORONES AND DERIVATIVES THEREOF | LEIBNIZ-INSTITUT FÜR PFLANZENBIOCHEMIE (IPB) (DE) | 2005-09-01 | — | — | WO | disclosed |