Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD4 | Q53EL6 | 2/20 | 0.39 |
| ▸ | GLS2 | Q9UI32 | 3/20 | 0.38 |
| ▸ | DNTT | P04053 | 2/20 | 0.34 |
| ▸ | GALR3 | O60755 | 1/20 | 0.34 |
| ▸ | PNLIP | P16233 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | POLA1 | P09884 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 4/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.32 |
| ▸ | PRKCG | P05129 | 1/20 | 0.32 |
| ▸ | PRKCB | P05771 | 1/20 | 0.32 |
| ▸ | PRKCH | P24723 | 1/20 | 0.32 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.32 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.32 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.32 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.31 |
| ▸ | TOP1 | P11387 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29970207 | 1.00 | PDCD4 (0.39) | PDCD4GLS2DNTTGALR3PNLIP | |
| SCHEMBL6505924 | 1.00 | PDCD4 (0.39) | PDCD4GLS2DNTTGALR3PNLIP | |
| SCHEMBL6504100 | 0.86 | PDCD4 (0.37) | PDCD4GLS2DNTTPOLBPOLA1 | |
| SCHEMBL6528851 | 0.85 | PDCD4 (0.42) | PDCD4GLS2DNTTGALR3POLB | |
| SCHEMBL6527430 | 0.75 | PDCD4 (0.36) | PDCD4GLS2DNTTPRKCAPRKD3 | |
| SCHEMBL6528438 | 0.73 | DNTT (0.36) | DNTTPOLBPOLA1PRKCAPRKD3 | |
| SCHEMBL6528440 | 0.73 | DNTT (0.36) | DNTTPOLBPOLA1PRKCAPRKD3 | |
| SCHEMBL6528441 | 0.73 | DNTT (0.36) | DNTTPOLBPOLA1PRKCAPRKD3 | |
| SCHEMBL30375807 | 0.67 | PDCD4 (0.40) | PDCD4DNTTPOLBDAGLATOP1 | |
| SCHEMBL18191881 | 0.67 | PDCD4 (0.40) | PDCD4DNTTPOLBDAGLATOP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005080311-A1 | HYGROPHORONES AND DERIVATIVES THEREOF | LEIBNIZ-INSTITUT FÜR PFLANZENBIOCHEMIE (IPB) (DE) | 2005-09-01 | — | — | WO | disclosed |