Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 17/20 | 0.44 |
| ▸ | PPARD | Q03181 | 12/20 | 0.44 |
| ▸ | PPARG | P37231 | 9/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6504220 | 1.00 | PPARA (0.44) | PPARAPPARDPPARGMMP1LMNA | |
| SCHEMBL6495628 | 0.91 | PPARA (0.45) | PPARAPPARDPPARGMMP1MAPT | |
| SCHEMBL6495621 | 0.91 | PPARA (0.45) | PPARAPPARDPPARGMMP1MAPT | |
| SCHEMBL6501017 | 0.89 | MMP1 (0.48) | PPARAPPARDPPARGMMP1LMNA | |
| SCHEMBL6501010 | 0.89 | MMP1 (0.48) | PPARAPPARDPPARGMMP1LMNA | |
| SCHEMBL6496110 | 0.87 | PPARA (0.42) | PPARAPPARDPPARGMMP1LMNA | |
| SCHEMBL6496109 | 0.87 | PPARA (0.42) | PPARAPPARDPPARGMMP1LMNA | |
| SCHEMBL6503176 | 0.85 | PPARA (0.41) | PPARAPPARDPPARGMMP1LMNA | |
| SCHEMBL6503180 | 0.85 | PPARA (0.41) | PPARAPPARDPPARGMMP1LMNA | |
| SCHEMBL6503992 | 0.84 | PPARA (0.46) | PPARAPPARDPPARGMMP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |