Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 0.61 |
| ▸ | ITGAV | P06756 | 20/20 | 0.61 |
| ▸ | ITGB1 | P05556 | 18/20 | 0.53 |
| ▸ | ITGA5 | P08648 | 18/20 | 0.53 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.46 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6490652 | 0.92 | ITGB3 (0.73) | ITGB3ITGAVITGB1ITGA5ITGB5 | |
| SCHEMBL6180607 | 0.79 | ITGB3 (0.74) | ITGB3ITGAVITGB1ITGA5ITGB5 | |
| SCHEMBL7512617 | 0.78 | ITGB3 (0.81) | ITGB3ITGAVITGB1ITGA5ITGB5 | |
| SCHEMBL27510388 | 0.78 | MAOB (0.53) | — | |
| SCHEMBL6178889 | 0.77 | ITGB3 (0.74) | ITGB3ITGAVITGB1ITGA5ITGB5 | |
| SCHEMBL6175847 | 0.77 | ITGB3 (0.74) | ITGB3ITGAVITGB1ITGA5ITGB5 | |
| SCHEMBL6175851 | 0.77 | ITGB3 (0.74) | ITGB3ITGAVITGB1ITGA5ITGB5 | |
| SCHEMBL6176294 | 0.77 | ITGB3 (0.73) | ITGB3ITGAVITGB1ITGA5ITGB5 | |
| SCHEMBL7797654 | 0.76 | ITGB3 (0.67) | ITGB3ITGAVITGB1ITGA5ITGB5 | |
| SCHEMBL7797657 | 0.76 | ITGB3 (0.67) | ITGB3ITGAVITGB1ITGA5ITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6881736-B1 | Vitronectin receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 2005-04-19 | — | — | US | disclosed |