Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | UGCG | Q16739 | 1/20 | 0.55 |
| ▸ | MTOR | P42345 | 1/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.55 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | GMNN | O75496 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4827097 | 1.00 | MEN1 (0.55) | MEN1KMT2ACYP2C19TP53CYP3A4 | |
| SCHEMBL6549161 | 0.81 | OPRM1 (0.47) | MEN1KMT2ACYP2C19TP53CYP3A4 | |
| SCHEMBL6550203 | 0.81 | SIRT2 (0.48) | MEN1KMT2ACYP2C19TP53CYP3A4 | |
| SCHEMBL6548454 | 0.81 | OPRM1 (0.46) | MEN1KMT2ACYP2C19TP53CYP3A4 | |
| SCHEMBL6549118 | 0.81 | OPRM1 (0.50) | MEN1KMT2ATP53MAPK1OPRM1 | |
| SCHEMBL21634178 | 0.78 | EPHX2 (0.52) | MEN1KMT2ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL7768218 | 0.78 | MEN1 (0.53) | MEN1KMT2ATP53MAPTOPRM1 | |
| SCHEMBL7771047 | 0.78 | MEN1 (0.55) | MEN1KMT2ACYP2C19TP53CYP3A4 | |
| SCHEMBL6548467 | 0.77 | OPRM1 (0.46) | MEN1KMT2ACYP2C19TP53CYP3A4 | |
| SCHEMBL17913115 | 0.76 | UGCG (0.56) | TP53MAPTUGCGOPRM1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6890949-B1 | Amino ceramide-like compounds and therapeutic methods of use | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2005-05-10 | — | — | US | disclosed |