Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6506951 | 0.85 | ADORA2B (1.00) | ADORA2BADORA2A | |
| SCHEMBL6503867 | 0.84 | ADORA2A (1.00) | ADORA2BADORA2A | |
| SCHEMBL6509058 | 0.83 | ADORA2B (1.00) | ADORA2BADORA2A | |
| SCHEMBL6505264 | 0.83 | ADORA2B (0.71) | ADORA2BADORA2A | |
| SCHEMBL24227597 | 0.82 | ADORA2B (1.00) | ADORA2BADORA2A | |
| SCHEMBL5741227 | 0.81 | ADORA2B (0.68) | ADORA2BADORA2A | |
| SCHEMBL6512294 | 0.80 | ADORA2B (0.79) | ADORA2BADORA2A | |
| SCHEMBL6511660 | 0.78 | ADORA2B (0.80) | ADORA2BADORA2A | |
| SCHEMBL6506235 | 0.76 | ADORA2B (1.00) | ADORA2BADORA2A | |
| SCHEMBL6505455 | 0.75 | ADORA2B (0.81) | ADORA2BADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050070558-A1 | 6-Phenyldihydropyrrolopyrimidinedione derivatives | ALMIRALL PRODESFARMA S.A. (ES) | 2005-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050070558-A1 | 6-Phenyldihydropyrrolopyrimidinedione derivatives | ADORA1, ADORA2A, P2RY10 | ADORA2B 4/4885ADORA2A 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.