Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 10/20 | 0.38 |
| ▸ | PPARG | P37231 | 8/20 | 0.38 |
| ▸ | PPARD | Q03181 | 8/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6498868 | 0.94 | PPARA (0.40) | PPARAPPARGPPARDMAOB | |
| SCHEMBL6506183 | 0.88 | PPARA (0.39) | PPARAPPARGPPARDMAOB | |
| SCHEMBL6502616 | 0.88 | PPARG (0.40) | PPARAPPARGPPARDTP53MAPT | |
| SCHEMBL6498964 | 0.85 | PPARA (0.39) | PPARAPPARGPPARDTP53MAOB | |
| SCHEMBL6495514 | 0.85 | PPARA (0.40) | PPARAPPARGPPARDMAOB | |
| SCHEMBL6505714 | 0.85 | NPC1 (0.41) | PPARAPPARGPPARDTP53MAPT | |
| SCHEMBL7676301 | 0.84 | PPARG (0.43) | PPARAPPARGPPARD | |
| SCHEMBL6504631 | 0.83 | PPARG (0.44) | PPARAPPARGPPARD | |
| SCHEMBL6496886 | 0.82 | PPARG (0.41) | PPARAPPARGPPARDTP53MAPT | |
| SCHEMBL6496860 | 0.81 | PPARG (0.49) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |