Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 11/20 | 0.39 |
| ▸ | PPARD | Q03181 | 10/20 | 0.39 |
| ▸ | PPARG | P37231 | 10/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | KIT | P10721 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6498868 | 0.91 | PPARA (0.40) | PPARAPPARDPPARGMAOB | |
| SCHEMBL6502616 | 0.90 | PPARG (0.40) | PPARAPPARDPPARGKDM4E | |
| SCHEMBL6504694 | 0.88 | PPARA (0.38) | PPARAPPARDPPARGMAOB | |
| SCHEMBL6498964 | 0.88 | PPARA (0.39) | PPARAPPARDPPARGMAOB | |
| SCHEMBL6495514 | 0.85 | PPARA (0.40) | PPARAPPARDPPARGMAOB | |
| SCHEMBL6505714 | 0.85 | NPC1 (0.41) | PPARAPPARDPPARGKDM4E | |
| SCHEMBL7676301 | 0.85 | PPARG (0.43) | PPARAPPARDPPARG | |
| SCHEMBL6504631 | 0.83 | PPARG (0.44) | PPARAPPARDPPARG | |
| SCHEMBL6496886 | 0.83 | PPARG (0.41) | PPARAPPARDPPARG | |
| SCHEMBL6496860 | 0.82 | PPARG (0.49) | PPARAPPARDPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |