Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 16/20 | 0.56 |
| ▸ | PPARA | Q07869 | 16/20 | 0.56 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | KDM4A | O75164 | 1/20 | 0.42 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6504759 | 1.00 | PPARG (0.56) | PPARGPPARAP2RX7KDM4EKDM4A | |
| SCHEMBL6510011 | 0.87 | PPARA (0.54) | PPARGPPARA | |
| SCHEMBL6510008 | 0.87 | PPARA (0.54) | PPARGPPARA | |
| SCHEMBL6508017 | 0.87 | PPARA (0.55) | PPARGPPARAGPR34 | |
| SCHEMBL6508014 | 0.87 | PPARA (0.55) | PPARGPPARAGPR34 | |
| SCHEMBL6505273 | 0.81 | PPARA (0.60) | PPARGPPARA | |
| SCHEMBL6505278 | 0.81 | PPARA (0.60) | PPARGPPARA | |
| SCHEMBL6504770 | 0.78 | PPARG (0.42) | PPARGPPARAP2RX7GPR34 | |
| SCHEMBL6511136 | 0.76 | PPARG (0.59) | PPARGPPARA | |
| SCHEMBL6511131 | 0.76 | PPARG (0.59) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040127-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2005-05-06 | — | — | WO | claimed |
| WO-2005040127-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2005-05-06 | — | — | WO | disclosed |