Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.48 |
| ▸ | STAT1 | P42224 | 1/20 | 0.48 |
| ▸ | TERT | O14746 | 4/20 | 0.36 |
| ▸ | TOP1 | P11387 | 4/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | CYCS | P99999 | 3/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4260277 | 0.91 | STAT3 (0.56) | STAT3STAT1TERTTOP1ABCG2 | |
| SCHEMBL4261963 | 0.90 | STAT3 (0.55) | STAT3STAT1TERTTOP1ABCG2 | |
| SCHEMBL12987775 | 0.89 | STAT3 (0.59) | STAT3STAT1TERTTOP1ABCG2 | |
| SCHEMBL93007 | 0.88 | STAT3 (0.56) | STAT3STAT1TERTTOP1ABCG2 | |
| SCHEMBL31127548 | 0.88 | STAT3 (0.58) | STAT3STAT1TERTTOP1ABCG2 | |
| SCHEMBL227423 | 0.88 | STAT3 (0.54) | STAT3STAT1TERTTOP1ABCG2 | |
| SCHEMBL31127544 | 0.88 | STAT3 (0.58) | STAT3STAT1TERTTOP1ABCG2 | |
| SCHEMBL30527240 | 0.86 | STAT3 (0.67) | STAT3STAT1TERTTOP1ABCG2 | |
| SCHEMBL78903 | 0.85 | STAT3 (0.56) | STAT3STAT1TERTTOP1ABCG2 | |
| SCHEMBL30527241 | 0.85 | STAT3 (0.66) | STAT3STAT1TERTTOP1ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6849730-B2 | Methods of making porphyrins and related compounds with Lewis acids | NORTH CAROLINA STATE UNIVERSITY (US) | 2005-02-01 | — | — | US | disclosed |
| US-20030096978-A1 | Methods of making porphyrins and related compounds with Lewis acids | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030096978-A1 | Methods of making porphyrins and related compounds with Lewis acids | DDT, LIG3, SHARPIN | STAT3 3690/4885STAT1 4534/4885TERT 374/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.