Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 0.69 |
| ▸ | ITGAV | P06756 | 19/20 | 0.69 |
| ▸ | ITGA2B | P08514 | 18/20 | 0.69 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.43 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6497993 | 0.89 | ITGB3 (0.76) | ITGB3ITGAVITGA2B | |
| SCHEMBL7216172 | 0.86 | ITGB3 (0.62) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL7216180 | 0.86 | ITGB3 (0.62) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL6964937 | 0.82 | ITGB3 (0.62) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL6964924 | 0.82 | ITGB3 (0.61) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL6016272 | 0.81 | ITGB3 (1.00) | ITGB3ITGAVITGA2B | |
| SCHEMBL6829353 | 0.80 | ITGB3 (0.63) | ITGB3ITGAVITGA2B | |
| SCHEMBL6868486 | 0.80 | ITGB3 (0.59) | ITGB3ITGAVITGA2BITGB1ITGB5 | |
| SCHEMBL6832543 | 0.80 | ITGB3 (0.62) | ITGB3ITGAVITGA2B | |
| SCHEMBL6831996 | 0.80 | ITGB3 (0.62) | ITGB3ITGAVITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6900318-B1 | 1,4,5,6-tetrahydropyrimidine derivative as a vitronectin inhibitor | AVENTIS PHARMA DEUTSCLAND GMBH (DE) | 2005-05-31 | — | — | US | disclosed |