Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 19/20 | 0.61 |
| ▸ | PPARD | Q03181 | 18/20 | 0.61 |
| ▸ | PPARG | P37231 | 17/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6503394 | 0.89 | PPARA (0.60) | PPARAPPARDPPARG | |
| SCHEMBL6496322 | 0.89 | PPARA (0.72) | PPARAPPARDPPARGSMN1; SMN2 | |
| SCHEMBL6505564 | 0.88 | PPARA (0.66) | PPARAPPARDPPARG | |
| SCHEMBL6502352 | 0.88 | PPARA (0.79) | PPARAPPARDPPARG | |
| SCHEMBL6495734 | 0.87 | PPARA (0.58) | PPARAPPARDPPARG | |
| SCHEMBL6504171 | 0.87 | PPARA (0.58) | PPARAPPARDPPARG | |
| SCHEMBL6502631 | 0.84 | PPARA (0.75) | PPARAPPARDPPARG | |
| SCHEMBL6498599 | 0.84 | PPARA (0.54) | PPARAPPARDPPARG | |
| SCHEMBL6506017 | 0.83 | PPARA (0.51) | PPARAPPARDPPARG | |
| SCHEMBL6502399 | 0.83 | PPARG (0.64) | PPARAPPARDPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |