Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 20/20 | 0.51 |
| ▸ | PPARD | Q03181 | 16/20 | 0.51 |
| ▸ | PPARG | P37231 | 12/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6060873 | 0.89 | PPARA (0.51) | PPARAPPARDPPARG | |
| SCHEMBL6060870 | 0.89 | PPARA (0.51) | PPARAPPARDPPARG | |
| SCHEMBL6504240 | 0.85 | PPARA (0.52) | PPARAPPARDPPARG | |
| SCHEMBL6494274 | 0.84 | PPARA (0.51) | PPARAPPARDPPARG | |
| SCHEMBL6505358 | 0.83 | PPARA (0.61) | PPARAPPARDPPARG | |
| SCHEMBL6496012 | 0.83 | PPARA (0.57) | PPARAPPARDPPARG | |
| SCHEMBL6503712 | 0.83 | PPARA (0.50) | PPARAPPARDPPARG | |
| SCHEMBL6504042 | 0.82 | PPARA (0.56) | PPARAPPARDPPARG | |
| SCHEMBL7683194 | 0.82 | PPARA (0.45) | PPARAPPARDPPARG | |
| SCHEMBL7683198 | 0.82 | PPARA (0.45) | PPARAPPARDPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| WO-2005016883-A2 | ACRYLAMIDE DERIVATIVES AS VLA-1 INTEGRIN ANTAGONISTS AND USES THEREOF | ICOS CORPORATION (US) | 2005-02-24 | — | — | WO | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |