Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6615988 | 1.00 | TSHR (0.41) | TSHRALDH1A1HPGDLMNATDP1 | |
| SCHEMBL650935 | 0.76 | TSHR (0.42) | TSHRALDH1A1HPGDLMNATDP1 | |
| SCHEMBL1912801 | 0.76 | TSHR (0.41) | TSHRALDH1A1HPGDLMNATDP1 | |
| SCHEMBL650936 | 0.76 | TSHR (0.41) | TSHRALDH1A1HPGDLMNATDP1 | |
| SCHEMBL6615990 | 0.75 | TSHR (0.41) | TSHRALDH1A1HPGDLMNATDP1 | |
| SCHEMBL652797 | 0.75 | TSHR (0.41) | TSHRALDH1A1HPGDLMNATDP1 | |
| SCHEMBL652798 | 0.75 | TSHR (0.41) | TSHRALDH1A1HPGDLMNATDP1 | |
| SCHEMBL648974 | 0.75 | TSHR (0.41) | TSHRALDH1A1HPGDLMNATDP1 | |
| SCHEMBL1912802 | 0.75 | TSHR (0.41) | TSHRALDH1A1HPGDLMNATDP1 | |
| SCHEMBL651962 | 0.73 | TSHR (0.54) | TSHRALDH1A1HPGDADORA3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 167 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230348453-A1 | HALOGENATED-HETEROARYL AND OTHER HETEROCYCLIC KINASE INHIBITORS, AND USES THEREOF | IOMX THERAPEUTICS AG (DE) | 2023-11-02 | — | — | US | claimed |
| US-11351178-B2 | Selective HDAC6 inhibitors | ITALFARMACO SPA (IT) | 2022-06-07 | — | — | US | claimed |
| US-20210387982-A1 | HETEROCYCLIC KINASE INHIBITORS AND USES THEREOF | IOMX THERAPEUTICS AG (DE) | 2021-12-16 | — | — | US | claimed |
| US-20210128577-A1 | Selective HDAC6 Inhibitors | ITALFARMACO S.P.A. (IT) | 2021-05-06 | — | — | US | claimed |
| EP-3643713-A1 | HETEROCYCLIC KINASE INHIBITORS AND USES THEREOF | iOmx Therapeutics AG (DE) | 2020-04-29 | — | — | EP | claimed |
| CN-110546140-A | selective HDAC6 inhibitors | ITALFARMACO SPA | 2019-12-06 | — | — | CN | claimed |
| EP-2513064-B1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR CONTROLLING BIOFILMS | UNIV LEUVEN KATH (BE) | 2018-07-04 | — | — | EP | claimed |
| US-8906915-B2 | Compounds, compositions, and methods for controlling biofilms | KATHOLIEKE UNIVERSITEIT LEUVEN, K.U.LEUVEN R&D (BE) | 2014-12-09 | — | — | US | claimed |
| US-20130029981-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR CONTROLLING BIOFILMS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2013-01-31 | — | — | US | claimed |
| US-20110301217-A1 | Selective Glycosidase Inhibitors and Uses Thereof | SIMON FRASER UNIVERSITY (CA) | 2011-12-08 | — | — | US | claimed |
| EP-1206444-A1 | COMPOUNDS THAT INHIBIT TRYPTASE ACTIVITY | Morphochem AG (DE) | 2002-05-22 | — | — | EP | claimed |
| WO-2001014320-A1 | COMPOUNDS THAT INHIBIT TRYPTASE ACTIVITY | MORPHOCHEM AG (DE) | 2001-03-01 | — | — | WO | claimed |
| US-6060453-A | Immunomodulatory, anti-inflammatory, and anti-proliferative compounds: 5,6-dideoxy, 5-amino derivatives of idose and 6-deoxy, 6-amino derivatives of glucose | GREENWICH PHARMACEUTICALS INCORPORATED (US) | 2000-05-09 | — | — | US | claimed |
| EP-0715519-A4 | IMMUNOMODULATORY, ANTI-INFLAMMATORY, AND ANTI-PROLIFERATIVE COMPOUNDS: 5,6-DIDEOXY, 5-AMINO DERIVATIVES OF IDOSE AND 6-DEOXY, 6-AMINO DERIVATIVES OF GLUCOSE | BOSTON LIFE SCIENCES INC (US) | 1998-10-07 | — | — | EP | claimed |
| EP-0715519-A1 | IMMUNOMODULATORY, ANTI-INFLAMMATORY, AND ANTI-PROLIFERATIVE COMPOUNDS: 5,6-DIDEOXY, 5-AMINO DERIVATIVES OF IDOSE AND 6-DEOXY, 6-AMINO DERIVATIVES OF GLUCOSE | Boston Life Sciences, Inc. (US) | 1996-06-12 | — | — | EP | claimed |
| WO-1994028910-A1 | IMMUNOMODULATORY, ANTI-INFLAMMATORY, AND ANTI-PROLIFERATIVE COMPOUNDS: 5,6-DIDEOXY, 5-AMINO DERIVATIVES OF IDOSE AND 6-DEOXY, 6-AMINO DERIVATIVES OF GLUCOSE | BOSTON LIFE SCIENCES, INC. (US) | 1994-12-22 | — | — | WO | claimed |
| US-5219857-A | Method of treating cognitive and related neural behavioral problems | AMERICAN CYANAMID COMPANY (US) | 1993-06-15 | — | — | US | claimed |
| US-5126340-A | Antidepressants | AMERICAN CYANAMID COMPANY (US) | 1992-06-30 | — | — | US | claimed |
| EP-0264773-A1 | 4,5-dihydro and 4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidines | AMERICAN CYANAMID COMPANY (US) | 1988-04-27 | — | — | EP | claimed |
| US-3950339-A | SUBSTITUTED-2-(PYRIMIDINYLTHIO)ACETAMIDOXIMES AND ACETONITRILES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-04-13 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110301217-A1 | Selective Glycosidase Inhibitors and Uses Thereof | ENGASE, OGA, GPI | TSHR 4410/4885ALDH1A1 1513/4885HPGD 1949/4885 |
| US-20210128577-A1 | Selective HDAC6 Inhibitors | HDAC6, HDAC1, HDAC3 | TSHR 4046/4885ALDH1A1 104/4885HPGD 1112/4885 |
| US-20130029981-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR CONTROLLING BIOFILMS | AZI2, NOD1, AADAC | TSHR 2004/4885ALDH1A1 373/4885HPGD 620/4885 |
| US-20210387982-A1 | HETEROCYCLIC KINASE INHIBITORS AND USES THEREOF | LCK, SRC, CILK1 | TSHR 3753/4885ALDH1A1 3214/4885HPGD 3917/4885 |
| US-20230348453-A1 | HALOGENATED-HETEROARYL AND OTHER HETEROCYCLIC KINASE INHIBITORS, AND USES THEREOF | ABL1, PRKDC, PRKACA | TSHR 2835/4885ALDH1A1 2606/4885HPGD 4581/4885 |
| US-11351178-B2 | Selective HDAC6 inhibitors | HDAC6, HDAC1, HDAC3 | TSHR 4015/4885ALDH1A1 119/4885HPGD 1007/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.