Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.61 |
| ▸ | HPGD | P15428 | 4/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | CES1 | P23141 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL350086 | 0.82 | ALDH1A1 (0.62) | ALDH1A1MEN1KMT2ACYP3A4HPGD | |
| SCHEMBL12125121 | 0.80 | ALDH1A1 (0.61) | ALDH1A1MEN1KMT2ACYP3A4HPGD | |
| SCHEMBL28102384 | 0.77 | MEN1 (0.52) | ALDH1A1MEN1KMT2ACYP3A4HPGD | |
| SCHEMBL260807 | 0.77 | KMT2A (0.62) | ALDH1A1MEN1KMT2ACYP3A4HPGD | |
| SCHEMBL5932634 | 0.76 | HPGD (0.68) | ALDH1A1MEN1KMT2ACYP3A4HPGD | |
| Hydrochloric Acid SCHEMBL259354 | 0.75 | KMT2A (0.60) | ALDH1A1MEN1KMT2ACYP3A4HPGD | |
| SCHEMBL23023262 | 0.74 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2ACYP3A4HPGD | |
| SCHEMBL6931635 | 0.74 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2ACYP3A4HPGD | |
| Bromide SCHEMBL10777716 | 0.74 | HPGD (0.65) | ALDH1A1MEN1KMT2ACYP3A4HPGD | |
| Hydrochloric Acid SCHEMBL9432569 | 0.74 | HPGD (0.65) | ALDH1A1MEN1KMT2ACYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005016883-A2 | ACRYLAMIDE DERIVATIVES AS VLA-1 INTEGRIN ANTAGONISTS AND USES THEREOF | ICOS CORPORATION (US) | 2005-02-24 | — | — | WO | disclosed |