Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2263219 | 0.84 | KMT2A (0.67) | KMT2AOPRK1MEN1HPGDHTT | |
| SCHEMBL29532414 | 0.84 | KMT2A (0.67) | KMT2AOPRK1MEN1HPGDHTT | |
| SCHEMBL11154554 | 0.81 | KMT2A (0.63) | KMT2AOPRK1MEN1HTTSMN1; SMN2 | |
| SCHEMBL27961421 | 0.81 | KMT2A (0.63) | KMT2AOPRK1MEN1L3MBTL1SMN1; SMN2 | |
| SCHEMBL7685903 | 0.81 | KMT2A (0.63) | KMT2AOPRK1MEN1HTTALDH1A1 | |
| SCHEMBL7686142 | 0.81 | KMT2A (0.59) | KMT2AOPRK1MEN1ALDH1A1ACHE | |
| SCHEMBL28133331 | 0.79 | KMT2A (0.60) | KMT2AOPRK1MEN1L3MBTL1SMN1; SMN2 | |
| SCHEMBL5873486 | 0.78 | KDM4E (0.54) | KMT2AOPRK1MEN1HTTSMN1; SMN2 | |
| SCHEMBL3763346 | 0.78 | LMNA (0.58) | KMT2AOPRK1MEN1HTTSMN1; SMN2 | |
| SCHEMBL2256399 | 0.78 | KMT2A (0.56) | KMT2AOPRK1MEN1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005035526-A1 | BICYCLIC COMPOUNDS AND THEIR THERAPEUTIC USE | ARGENTA DISCOVERY LTD. (GB) | 2005-04-21 | — | — | WO | disclosed |