SCHEMBL650571

SCHEMBL650571

O=C(c1ccccc1)C(O)(F)c1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CES1 P23141 4/20 0.61
SRC P12931 1/20 0.46
PTPN1 P18031 2/20 0.44
CES2 O00748 3/20 0.44
ACHE P22303 1/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
TSHR P16473 2/20 0.42
ALDH1A1 P00352 2/20 0.42
DAO P14920 1/20 0.42
NAPRT Q6XQN6 1/20 0.42
LMNA P02545 1/20 0.42
SRD5A2 P31213 1/20 0.41
P2RX1 P51575 1/20 0.41
MAOB P27338 1/20 0.40
NR1H2 P55055 1/20 0.40
NR1H3 Q13133 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16147056 0.80 CES1 (0.64) CES1PTPN1CES2ACHENPC1
SCHEMBL3669363 0.79 CYP1A2 (0.50) CES1PTPN1RAB9ATSHRALDH1A1
SCHEMBL1826935 0.79 CYP1A2 (0.50) CES1PTPN1RAB9ATSHRALDH1A1
SCHEMBL680607 0.79 CES1 (0.57) CES1SRCPTPN1CES2ACHE
SCHEMBL242506 0.77 CES1 (0.54) CES1SRCCES2TSHRALDH1A1
SCHEMBL252920 0.77 CES1 (0.54) CES1SRCCES2TSHRALDH1A1
SCHEMBL1079930 0.77 CES1 (0.54) CES1SRCCES2TSHRALDH1A1
SCHEMBL562162 0.77 CES1 (0.54) CES1SRCCES2TSHRALDH1A1
SCHEMBL33083 0.77 CES1 (1.00) CES1CES2ACHETSHRALDH1A1
Benzene SCHEMBL27672585 0.77 CES1 (1.00) CES1CES2ACHETSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 528 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110372653-A A kind of selenizing benzofuran compound and its synthetic method 温州大学 2019-10-25 CN claimed
CN-109928945-A A kind of 1- bromine dibenzofurans and its synthetic method 西安欧得光电材料有限公司 2019-06-25 CN claimed
CN-109467662-A A kind of RTM type boron bakelite resin and preparation method thereof 北京玻钢院复合材料有限公司 2019-03-15 CN claimed
CN-109456571-A A kind of heat molten type boron bakelite resin and preparation method thereof 北京玻钢院复合材料有限公司 2019-03-12 CN claimed
CN-108947888-A A method of palladium chtalyst synthesis 3- replaces isoindolinone in water phase 南京理工大学 2018-12-07 CN claimed
CN-108440599-A The Pd-PEPPSI-NHC complexs and purposes of series base group modification containing high steric hindrance 天津师范大学 2018-08-24 CN claimed
CN-105753835-B Method for synthesizing 2- (4-fluorophenyl) thiophene 黑龙江鑫创生物科技开发有限公司 2018-06-12 CN claimed
CN-108017624-A The structure and its synthetic method of puerarin derivate 潘嘉慧 2018-05-11 CN claimed
CN-108004372-A High calcium aluminium slag ball and preparation method thereof 天津基纳科技发展有限公司 2018-05-08 CN claimed
CN-104628653-B The method of synthesizing rosuvastatin spit of fland calcium key intermediate 湖北益泰药业有限公司 2018-04-03 CN claimed
CN-1974616-A Polyacrylate compound and its prepn process and application in liquid crystal composition SHANGHAI FUXIAN PHOTOELECTRONI (CN) 2007-06-06 CN claimed
CN-1911880-A Multifluoro substituted diphenyl acetylene derivative, composition containing multifluoro substituted diphenyl acetylene derivatire, its preparation method and use SHIJIAZHUANG YONGSHENGHUAQING (CN) 2007-02-14 CN claimed
CN-1273473-C 3,5-difluoro-4-cyan benzene boric acid ester compound, preparing process thereof and application in liquid crystal composition SHIJIAZHUANG YONGSHENG HUASING (CN) 2006-09-06 CN claimed
CN-1733676-A 4-(4-n-alkyl)phenyl-3,5(or2,3)-difluoro-1',1'-difluorobenzyl-3,4,5-trifluorophenyl ether preparation method SHANGHAI KANGPENG CHEMICAL CO (CN) 2006-02-15 CN claimed
CN-1504470-A 3,5-difluoro-4-cyan benzene boric acid ester compound, preparing process thereof and application in liquid crystal composition 石家庄实力克液晶材料有限公司 2004-06-16 CN claimed
WO-2002067304-A1 A METHOD OF FORMING RESIST PATTERNS IN A SEMICONDUCTOR DEVICE AND A SEMICONDUCTOR WASHING LIQUID USED IN SAID METHOD HYON MAN-SOK (KR) 2002-08-29 WO claimed
EP-0788314-B1 NONDIGESTIBLE FAT COMPOSITIONS CONTAINING DIVERSELY ESTERIFIED POLYOL POLYESTERS FOR PASSIVE OIL LOSS CONTROL PROCTER & GAMBLE (US) 2001-09-12 EP claimed
EP-0788314-A1 NONDIGESTIBLE FAT COMPOSITIONS CONTAINING DIVERSELY ESTERIFIED POLYOL POLYESTERS FOR PASSIVE OIL LOSS CONTROL THE PROCTER & GAMBLE COMPANY (US) 1997-08-13 EP claimed
US-5480667-A CONTAING NONDIGESTIBLE SOLID POLYOL ESTERS OF SPECIFIED CARBON CHAIN LENGTH FATTY ACID DISPERSED IN LIQUID NONDIGESTIBLE OIL; POTATO CHIPS CORRIGAN PATRICK J (US) 1996-01-02 US claimed
WO-1994009639-A1 NONDIGESTIBLE FAT COMPOSITIONS CONTAINING DIVERSELY ESTERIFIED POLYOL POLYESTERS FOR PASSIVE OIL LOSS CONTROL THE PROCTER & GAMBLE COMPANY (US) 1994-05-11 WO claimed